791009-51-3Relevant articles and documents
Preparation method of series of dioxane quinazoline derivatives
-
, (2020/06/20)
The invention discloses a preparation method of a series of dioxane quinazoline derivatives, and belongs to the field of drug intermediate synthesis. The route is mild in reaction conditions, and compared with a reported route, the steps are simpler, and the yield is higher. Specifically, the R group is methyl, ethyl, propyl, isopropyl, methoxyethyl, ethoxypropyl, N, N-dimethylaminopropyl, tetrahydrofuran-3-oxy, 1-methylpiperidine-4-methyl, 3-pyrrolidine propyl, 3-cyclohexylpropoxy, or N, 4-dimethylpiperidine-1-formamido.