791009-51-3Relevant academic research and scientific papers
Preparation method of series of dioxane quinazoline derivatives
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, (2020/06/20)
The invention discloses a preparation method of a series of dioxane quinazoline derivatives, and belongs to the field of drug intermediate synthesis. The route is mild in reaction conditions, and compared with a reported route, the steps are simpler, and the yield is higher. Specifically, the R group is methyl, ethyl, propyl, isopropyl, methoxyethyl, ethoxypropyl, N, N-dimethylaminopropyl, tetrahydrofuran-3-oxy, 1-methylpiperidine-4-methyl, 3-pyrrolidine propyl, 3-cyclohexylpropoxy, or N, 4-dimethylpiperidine-1-formamido.
4-HETEROARYL SUBSTITUTED BENZOIC ACID COMPOUNDS AS RORgammaT INHIBITORS AND USES THEREOF
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Page/Page column 65, (2014/03/22)
The present invention relates to compounds according to Formula I (Formula I), and pharmaceutically acceptable salts or solvates thereof. Such compounds can be used in the treatment of RORgammaT-mediated diseases or conditions.
