79121-34-9Relevant academic research and scientific papers
Sulfone Group as a Versatile and Removable Directing Group for Asymmetric Transfer Hydrogenation of Ketones
Clarkson, Guy J.,Vyas, Vijyesh K.,Wills, Martin
, p. 14265 - 14269 (2020/07/04)
The sulfone functional group has a strong capacity to direct the asymmetric transfer hydrogenation (ATH) of ketones in the presence of [(arene)Ru(TsDPEN)H] complexes by adopting a position distal to the η6-arene ring. This preference provides a
Catalytic Asymmetric [4 + 1] Annulation of Sulfur Ylides with Copper-Allenylidene Intermediates
Wang, Qiang,Li, Tian-Ren,Lu, Liang-Qiu,Li, Miao-Miao,Zhang, Kai,Xiao, Wen-Jing
supporting information, p. 8360 - 8363 (2016/07/27)
The first copper-catalyzed asymmetric decarboxylative [4 + 1] cycloaddition of propargylic carbamates and sulfur ylides was successfully developed. This strategy led to a series of chiral indolines with synthetically flexible alkyne groups in good yields and with high enantio- and diastereoselectivities (up to 99% yield, 98% ee, and >95:5 dr). A possible mechanism and stereoinduction mode with copper-allenylidenes were proposed as the possible dipolar intermediate.
Enantioselective synthesis of α-hydroxy thioesters via oxazaborolidine- mediated reduction of α-phenylthio enones
Berenguer, Ramon,Cavero, Marta,Garcia, Jordi,Munoz, Montse
, p. 2183 - 2186 (2007/10/03)
α-Phenylthio-α,β-alkenones (2), readily available by Pd(II)-catalysed coupling of (E)-1 phenylthio-1-tributylstannylhex-1-ene with the corresponding acid chlorides have been treated with borane in the presence of phenylglycine- or proline-derived oxazaborolidines to afford 2-phenylthio-2- alken-1-ols (3) with good to excellent enantioselectivities. Ozonolysis of 3 provides a new and efficient route to chiral α-hydroxy thioesters 4.
ELECTROREDUCTIVE CLEAVAGE OF CARBON-SULPHUR BONDS IN DITHIOACETALS
Itter, Nicola Schultz-von,Steckhan, Eberhard
, p. 2475 - 2484 (2007/10/02)
The carbon-sulphur bond in aliphatic diphenyldithioacetals, α-carbonyldiphenyldithioacetals and α-carbonylketene dimethyldithioacetals can be cleaved cathodically on mercury (Hg) or glassy carbon (GC) electrodes.In the presence of tetrabutylammoniumhydrog
