66080-23-7 Usage
Uses
Used in Chemical Synthesis:
4,4,5,5-Tetramethyl-2-phenylsulfanylmethyl-1,3,2-dioxaborolane is used as a versatile reagent for the preparation of aryl and heteroaryl derivatives. Its ability to form C-C and C-hetero bonds makes it a valuable component in the synthesis of complex organic molecules and pharmaceutical compounds.
Used in Pharmaceutical Industry:
As a starting material in the synthesis of α-aminoboronic acids, 4 4 5 5-TETRAMETHYL-2-PHENYLSULFANYLMET& plays a crucial role in the development of serine protease inhibitors. These inhibitors are important in the treatment of various diseases, including cancer and inflammatory conditions, by modulating the activity of specific enzymes involved in these pathological processes.
Used in Catalysis:
4,4,5,5-Tetramethyl-2-phenylsulfanylmethyl-1,3,2-dioxaborolane also serves as a substrate in coupling reactions with carbonyl compounds under iridium (Ir)-catalyzed photoredox conditions. This application allows for the efficient formation of new chemical bonds and the synthesis of a wide range of organic compounds, further expanding the utility of 4 4 5 5-TETRAMETHYL-2-PHENYLSULFANYLMET& in various chemical and pharmaceutical applications.
Check Digit Verification of cas no
The CAS Registry Mumber 66080-23-7 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 6,6,0,8 and 0 respectively; the second part has 2 digits, 2 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 66080-23:
(7*6)+(6*6)+(5*0)+(4*8)+(3*0)+(2*2)+(1*3)=117
117 % 10 = 7
So 66080-23-7 is a valid CAS Registry Number.
InChI:InChI=1/C13H19BO2S/c1-12(2)13(3,4)16-14(15-12)10-17-11-8-6-5-7-9-11/h5-9H,10H2,1-4H3
66080-23-7Relevant academic research and scientific papers
Strategic Trimethylsilyldiazomethane Insertion into pinB-SR Followed by Selective Alkylations
Civit, Marc G.,Royes, Jordi,Vogels, Christopher M.,Westcott, Stephen A.,Cuenca, Ana B.,Fernández, Elena
, p. 3830 - 3833 (2016/08/16)
The insertion of the diazo derivative Me3SiCHN2 into pinB-SR σ bonds (R = Ph, Tol, Bn) allows a direct synthesis of multisubstituted H-C(SR)(Bpin)(SiMe3) compounds. Consecutive base-assisted transformations of HC(S)(B) (Si
Carbanlons from α-phenylthio boronic esters as synthetic intermediates
Matteson, Donald S.,Arne, Karl H.
, p. 280 - 288 (2008/10/08)
(Phenylthio)methaneboronic acid (1) was easily prepared from (phenylthio)methyllithium and trimethyl borate and was converted to boronic esters 2.
