79141-08-5

Upstream product

• 79141-11-0 (S)-2-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-succinic acid 4-benzyl ester 1-(2,5-dioxo-pyrrolidin-1-yl) ester 
• 147-85-3 L-proline 
• 13734-41-3 t-Boc-L-valine 
• 2177-63-1 (S)-2-amino-4-(benzyloxy)-4-oxobutanoic acid 
• 3392-12-9 Boc-valine N-hydroxysuccinimide ester 

Downstream Products

• 79141-11-0 (S)-2-((S)-2-tert-Butoxycarbonylamino-3-methyl-butyrylamino)-succinic acid 4-benzyl ester 1-(2,5-dioxo-pyrrolidin-1-yl) ester 

Relevant academic research and scientific papers

Synthesis and properties of myelopeptides possessing differentiating activity

Bone marrow peptides Phe-Arg-Pro-Arg-Ile-Met-Thr-Pro (MP-4) and Val-Asp-Pro-Pro (MP-6) have been synthesized y the classical and solid-phase methods of peptide chemistry, and their differentiatingactivity has been studied on leukemia cell ines HL-60 and K-562. It has been shown that both peptides induce the terminal differentiation of leukemic blasts; however, their echanisms of action are different. Pleiades Publishing, Ltd., 2010.