79149-50-1Relevant academic research and scientific papers
A facile one-carbon homologation of aryl aldehydes to amides.
Shen, Wang,Kunzer, Aaron
, p. 1315 - 1317 (2002)
The easily accessible 2-aryl-1,1-dibromo-1-alkenes can be converted to amides under unusually mild conditions in good to excellent yields. Both electron-donating and electron-withdrawing substitutions on the aromatic rings are tolerated, and the reaction works well with hindered alkylamines. This simple homologation could find broad applications. [reaction: see text]
