791644-01-4

Upstream product

• 59557-91-4 4-bromo-2-methoxyaniline 
• 791642-68-7 4-bromo-1-iodo-2-methoxybenzene 
• 905815-92-1 5-bromo-2-(3-fluoro-phenylsulfanyl)-phenol 
• 905815-85-2 5-bromo-2-(3-fluoro-phenylsulfanyl)-1-methoxybenzene 
• 905816-01-5 2-[5-bromo-2-(3-fluoro-phenylsulfanyl)-phenoxy]-ethanol 
• 2812-46-6 proline tert-butyl ester 

Relevant academic research and scientific papers

The synthesis and SAR of 2-arylsulfanylphenyl-1-oxyalkylamino acids as GlyT-1 inhibitors

Elevation of glycine levels by inhibition of the glycine transporter-1 (GlyT-1) and activation of the NMDA receptor is a potential strategy for the treatment of schizophrenia. A novel series of 2-arylsulfanylphenyl-1-oxyalkyl amino acids have been identif

AROMATIC OXYPHENYL AND AROMATIC SYLFANYLPHENYL DERIVATIVES

The present invention relates to compounds of formula I wherein the substituents are as defined below. The compounds of formula I are useful for the treatment of diseases such as schizophrenia, including both the positive and the negative symptoms of schizophrenia and other psychoses.