79174-57-5

Upstream product

• 536-38-9 4-chlorobenzoylmethyl bromide 
• 58905-19-4 1-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanone 

Downstream Products

• 1113018-12-4 3-(4-chlorophenyl)-2-(1H-1,2,4-triazol-1-yl)-2H-benzo[b][1,4]thiazine 
• 1278594-58-3 C₂₆H₁₇Cl₃N₆S 
• 1278594-61-8 C₂₇H₂₀Cl₂N₆OS 
• 1278594-46-9 C₂₆H₁₉ClN₆S 
• 1278594-49-2 C₂₆H₁₈Cl₂N₆S 
• 1278594-55-0 C₂₆H₁₈Cl₂N₆S 
• 1278594-52-7 C₂₇H₂₁ClN₆OS 
• 384859-90-9 4-(4-chloro-phenyl)-5-[1,2,4]triazol-1-yl-thiazol-2-ylamine 

Relevant academic research and scientific papers

Synthesis and Antimicrobial Activity of Novel 2-Substituted Phenoxy-N-(4-substituted Phenyl-5-(1H-1,2,4-triazol-1-yl)thiazol-2-yl)acetamide Derivatives

A series of 2-substituted phenoxy-N-(4-substituted phenyl-5-(1H-1,2,4-triazol-1-yl)thiazole-2-yl)acetamide derivatives 8a, 8b, 8c, 8d, 8e, 8f, 8g, 8h, 8i, 8j, 8k, 8l, 8m, 8n, 8o, 8p, 8q, 8r, 8s, 8t was synthesized by the reaction of phenoxyacetyl chloride 7 with intermediate 4-substituted phenyl-5-(1H-1,2,4-triazol-1-yl)thiazol-2-amine 5. Their structures were confirmed by 1H NMR, 13C NMR, MS, IR, and elemental analyses. The synthesized compounds were also screened for their antimicrobial activity against three types of plant fungi (Gibberella zeae, Phytophthora infestans, and Paralepetopsis sasakii) and two kinds of bacteria [Xanthomonas oryzae pv. oryzae (Xoo) and Xanthomonas axonopodis pv. citri (Xac)] showing promising results. In particular, 8b, 8f, 8g, and 8h exhibited excellent antibacterial activity against Xoo, with 50% effective concentration (EC50) values of 35.2, 80.1, 62.5, and 82.1 μg/mL, respectively, which are superior to the commercial antibacterial agent bismerthiazol (89.9 μg/mL). The preliminary structure–activity relationship studies of these compounds are also briefly described.

Synthesis and crystal structure of new thiazolyl-pyrazoline derivatives bearing 1,2,4-triazole moiety

The title compounds 1-(4-aryl-5-triazolyl-2-thiazolyl)-3,5-diaryl-2- pyrazoline derivatives (3a-c) were synthesized by reacting 3,5-diaryl1- thiocarbamoyl -2-pyrazoline 1 with 2-bromo-1-aryl-2-(1H-1,2,4-triazol-1-yl) ethanones 2 in boiling ethanol. Their

Synthesis and spectral characterization of some new thiazolyl-pyrazolines bearing 1,2,4-triazole moiety

Chemical Equation Presented In this study, several new 1-(4-aryl-5- triazolyl-2-thiazolyl)-3,5-diaryl-2-pyrazolines (3a-r) were synthesized by reacting 3,5-diaryl1-thiocarbamoyl-2-pyrazolines (1) with 2-bromo-1-aryl-2-(1H- 1,2,4-triazol-1-yl) ethanones (2) in boiling ethanol. The chemical structures of the compounds were verified by IR, 1H NMR, ESI-MS spectroscopic data, and elemental analyses. Copyright Taylor & Francis Group, LLC.

A convenient synthesis of 2-(1 H- 1,2,4-triazol-1-yl)-2H-1, 4-benzothiazine derivatives

A series of 2-(1H-1,2,4-triaZol-1-yl)-2H-1, 4-benzothiazines were designed and synthesized by condensation of 1,2,4-triazole-substituted ω-bromoacetophenones and o-aminothiophenols with the aid of K 2CO3 under mild conditions with moderate to high yields.

Combatting fungi with triazolylphenacyl pyridyl ether derivatives

Triazolylphenacyl pyridyl ether derivatives of the formula STR1 in which R is optionally substituted phenyl, X is --CO-- or CH(OH)--, Y each independently is halogen, alkyl, alkoxy or cyano, and n is 0, 1, 2, 3 or 4, or a physiologically acceptable additi