791823-70-6

Basic information

• Product Name: N-(4-imidazol-1-yl-2-nitro-5-trifluoromethyl-phenyl)-N-(4-methoxy-benzyl)-acetamide
• CAS NO: 791823-70-6
• Molecular Weight: 434.375
• Mol File: 791823-70-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: N-(4-imidazol-1-yl-2-nitro-5-trifluoromethyl-phenyl)-N-(4-methoxy-benzyl)-acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-imidazol-1-yl-2-nitro-5-trifluoromethyl-phenyl)-N-(4-methoxy-benzyl)-acetamide(791823-70-6)
• EPA Substance Registry System: N-(4-imidazol-1-yl-2-nitro-5-trifluoromethyl-phenyl)-N-(4-methoxy-benzyl)-acetamide(791823-70-6)

Safety Data

• Hazardous Substances Data: 791823-70-6(Hazardous Substances Data)

Upstream product

• 400-74-8 2-Fluoro-5-nitrobenzotrifluoride 
• 143151-01-3 4-fluoro-2-nitro-5-(trifluoromethyl)acetanilide 
• 2145-38-2 4-fluoro-3-(trifluoromethyl)acetanilide 
• 288-32-4 1H-imidazole 
• 791823-69-3 N-(4-fluoro-2-nitro-5-trifluoromethyl-phenyl)-N-(4-methoxy-benzyl)-acetamide 

Downstream Products

• 143151-06-8 4-(1H-imidazol-1-yl)-5-(trifluoromethyl)-2-nitroaniline 

Relevant articles and documents

Synthesis and AMPA receptor antagonistic activity of a novel 7-imidazolyl-6-trifluoromethyl quinoxalinecarboxylic acid with a substituted phenyl group and improved its good physicochemical properties by introduced CF3 group

We describe the synthesis, physicochemical and biological properties of a novel series of 7-imidazolyl-6-trifluoromethyl quinoxalinecarboxylic acids with a substituted phenyl group. Among them, compound 9k (KRP-199) was found to possess high potency and selectivity for the AMPA-R and to exhibit good neuroprotective effects in vivo, and also showed good physicochemical properties by introduced trifluoromethyl group at the C-6 position.