791846-34-9Relevant academic research and scientific papers
Synthesis and activity of 2-[4-(4-[3H]-2-cyanophenyl) piperazinyl]-N-(2,4,6-[3H]3-3-methylphenyl)acetamide: A selective dopamine D4 receptor agonist and radioligand
Matulenko, Mark A.,Surber, Bruce,Fan, Leimin,Kolasa, Teodozyi,Nakane, Masaki,Terranova, Marc A.,Uchic, Marie E.,Miller, Loan N.,Chang, Renjie,Donnelly-Roberts, Diana L.,Namovic, Marian T.,Moreland, Robert B.,Brioni, Jorge D.,Stewart, Andrew O.
, p. 5095 - 5098 (2004)
The first selective dopamine D4 agonist radioligand is described. The synthesis of these piperazine radioligands relied on the transformation of brominated precursors 4a and 4b with tritium gas in the presence of a sensitive cyano functional gr
