791846-40-7

Basic information

• Product Name: 1-BOC-4-(4-BROMO-2-CYANOPHENYL)PIPERAZINE
• Synonyms: 1-BOC-4-(4-BROMO-2-CYANOPHENYL)PIPERAZINE;TERT-BUTYL 4-(4-BROMO-2-CYANOPHENYL)PIPERAZINE-1-CARBOXYLATE;tert-Butyl 4-(4-bromo-2-cyanophenyl);4-(4-Bromo-2-cyano-phenyl)-piperazine-1-carboxylic acid tert-butyl ester
• CAS NO: 791846-40-7
• Molecular Formula: C₁₆H₂₀BrN₃O₂
• Molecular Weight: 366.27
• Mol File: 791846-40-7.mol
• Article Data: 6

Chemical Properties

• Boiling Point: 471.679°C at 760 mmHg
• Flash Point: 239.063°C
• Appearance: /
• Density: 1.42g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.6
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: 1-BOC-4-(4-BROMO-2-CYANOPHENYL)PIPERAZINE(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BOC-4-(4-BROMO-2-CYANOPHENYL)PIPERAZINE(791846-40-7)
• EPA Substance Registry System: 1-BOC-4-(4-BROMO-2-CYANOPHENYL)PIPERAZINE(791846-40-7)

Safety Data

• Hazardous Substances Data: 791846-40-7(Hazardous Substances Data)

Usage

General Description

1-BOC-4-(4-BROMO-2-CYANOPHENYL)PIPERAZINE is a chemical compound that belongs to the piperazine class of organic compounds. It is derived from piperazine, a six-membered heterocyclic compound containing two nitrogen atoms. 1-BOC-4-(4-BROMO-2-CYANOPHENYL)PIPERAZINE is functionalized with a BOC protecting group, which helps to maintain the reactivity of the piperazine ring while protecting it from unwanted reactions. Additionally, it contains a bromo and a cyano group on the phenyl ring, which can make it suitable for various chemical reactions and derivatizations. 1-BOC-4-(4-BROMO-2-CYANOPHENYL)PIPERAZINE has potential applications in pharmaceutical and chemical research due to its unique structure and reactivity.

InChI:InChI=1/C16H20BrN3O2/c1-16(2,3)22-15(21)20-8-6-19(7-9-20)14-5-4-13(17)10-12(14)11-18/h4-5,10H,6-9H2,1-3H3

Upstream product

• 179897-89-3 5-Bromo-2-fluoro-benzonitrile 
• 57260-71-6 1-t-Butoxycarbonylpiperazine 

Downstream Products

• 1163248-80-3 2-(4-(4-bromo-2-cyanophenyl)piperazin-1-yl)-N,N-diethyl-2-phenylacetamide 
• 791846-35-0 2-[4-(4-bromo-2-cyano-phenyl)-piperazin-1-yl]-N-(2,4,6-tribromo-3-methyl-phenyl)-acetamide 
• 791846-34-9 2-[4-(4-bromo-2-cyano-phenyl)-piperazin-1-yl]-N-(4-bromo-3-methyl-phenyl)-acetamide 
• 791846-41-8 5-bromo-2-piperazin-1-yl-benzonitrile 

Relevant articles and documents

Thiazolidine derivatives or salts thereof as an active ingredient an inhibitor Pim

PROBLEM TO BE SOLVED: To provide compounds which have excellent Pim inhibitory action and are useful as pharmaceuticals.SOLUTION: A compound is a thiazolidine derivative represented by the general formula (1) in the figure, or a salt thereof. (In the formula, X represents O or S; Rrepresents a hydrogen atom or a Calkyl group; Z, Z, Z, Z, Zand Zeach independently represent CH or N; Y represents an optionally substituted, divalent Caromatic hydrocarbon group or the like; Am represents a disubstituted amino group, or an optionally substituted, nitrogen-containing saturated heterocyclic group; and Rand Reach independently represent a hydrogen atom, a halogen atom, an alkyl group or the like.)

SYK INHIBITORS

The present disclosure a Syk compound inhibitors, including state cancer and inflammation and various disease States thereof in the treatment of relates to the use of. In one aspect a particular embodiment, . given by formula I which is marked as a chemical structure of compound. In formula said, X 1, X 2, X 3, R 2, R 3, R 4, R 5, and Y has described herein is. The present disclosure of a formula I compounds or a pharmaceutically acceptable salt of pharmaceutical compositions including, mediated by Syk and to treat conditions a employing these compounds and compositions further provides a method. (by machine translation)

PIPERAZINYL DERIVATIVES USEFUL AS MODULATORS OF THE NEUROPEPTIDE Y2 RECEPTOR

The present invention is directed to piperidinyl and piperazinyl derivatives of formula (I) useful as inhibitors of the NPY Y2 receptor, pharmaceutical compositions comprising said compounds, processes for the preparation of said compounds and the use of