792122-33-9

Usage

Chemical structure

A complex compound consisting of a quinolinone ring with a dihydro-3-methyl-3-[3-(methylamino)propyl]-1-phenylsubstituent.

Pharmaceutical applications

Has potential applications in the pharmaceutical industry due to its diverse biological activities, including anti-inflammatory, anti-tumor, and antibacterial properties.

Neurodegenerative and psychiatric disorders

The compound has been studied for its potential role in the treatment of neurodegenerative diseases and psychiatric disorders.

Precursor in synthesis

It is used as a precursor in the synthesis of various organic compounds.

Unique structure

The compound has a unique structure that contributes to its diverse pharmacological properties.

Interest in medicinal chemistry

The structure and properties make it an interesting target for further research and development in the field of medicinal chemistry.

Upstream product

• 868701-22-8 1-(4-methoxy-benzyl)-3-methyl-3-(3-methylamino-propyl)-3,4-dihydro-1H-quinolin-2-one 
• 868701-30-8 3-(3-hydroxy-propyl)-1-(4-methoxy-benzyl)-3-methyl-3,4-dihydro-1H-quinolin-2-one 
• 868701-21-7 methyl-[3-(3-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl)-propyl]-carbamic acid tert-butyl ester 
• 792122-86-2 3-allyl-1-(4-methoxy-benzyl)-3-methyl-3,4-dihydro-1H-quinolin-2-one 
• 792122-90-8 3-methyl-3-(3-methylamino-propyl)-3,4-dihydro-1H-quinolin-2-one 
• 792122-85-1 1-[(4-methoxyphenyl)methyl]-3-methyl-3,4-dihydroquinolin-2-one 
• 792122-84-0 1-[(4-methoxyphenyl)methyl]-3,4-dihydroquinolin-2-one 
• 553-03-7 3,4-dihydro-2(1H)-quinolone 
• 868701-31-9 methanesulfonic acid 3-[1-(4-methoxy-benzyl)-3-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]-propyl ester 

Relevant academic research and scientific papers

1-Aryl-3,4-dihydro-1H-quinolin-2-one derivatives, novel and selective norepinephrine reuptake inhibitors

A novel series of 1-aryl-3,4-dihydro-1H-quinolin-2-ones have been discovered as potent and selective norepinephrine reuptake inhibitors. Efficient synthetic routes have been developed which allow for the multi-gram preparation of both final targets and ad

TREATMENT OF LEARNING DISABILITIES AND MOTOR SKILLS DISORDER WITH NOREPINEPHRINE REUPTAKE INHIBITORS

Provided are methods and medicaments for treating a learning disability or a Motor Skills Disorder, comprising administering to a patient in need of such treatment an effective amount of a selective norepinephrine reuptake inhibitor.

TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH NOREPINEPHRINE REUPTAKE INHIBITORS

Provided are methods and medicaments for treating a Pervasive Developmental Disorder, comprising administering to a patient in need of such treatment an effective amount of a selective norepinephrine reuptake inhibitor.

TREATMENT OF HOT FLASHES, IMPULSE CONTROL DISORDERS AND PERSONALITY CHANGE DUE TO A GENERAL MEDICAL CONDITION

Selective norepinephrine reuptake inhibitors are useful for the prevention or treatment of hot flashes, vasomotor symptoms, impulse control disorders or personality change due to a general medical condition.

QUINOLONE DERIVATIVES

This invention relates to compounds of formula (I) where -X-, n, R1, R3 and Ar- have the values defined herein, their preparation and use as norepinephrine reuptake inhibitors useful for the treatment of nervous system disorders