792122-86-2

Upstream product

• 792122-85-1 1-[(4-methoxyphenyl)methyl]-3-methyl-3,4-dihydroquinolin-2-one 
• 106-95-6 allyl bromide 
• 792122-84-0 1-[(4-methoxyphenyl)methyl]-3,4-dihydroquinolin-2-one 
• 824-94-2 p-methoxybenzyl chloride 
• 553-03-7 3,4-dihydro-2(1H)-quinolone 

Downstream Products

• 792122-87-3 3-(3-hydroxy-propyl)-1-(4-methoxy-benzyl)-3-methyl-3,4,4a,8a-tetrahydro-1H-quinolin-2-one 
• 868701-31-9 methanesulfonic acid 3-[1-(4-methoxy-benzyl)-3-methyl-2-oxo-1,2,3,4-tetrahydro-quinolin-3-yl]-propyl ester 
• 792122-57-7 6-chloro-3-methyl-3-(3-methylamino-propyl)-1-p-tolyl-3,4-dihydro-1H-quinolin-2-one 
• 868701-22-8 1-(4-methoxy-benzyl)-3-methyl-3-(3-methylamino-propyl)-3,4-dihydro-1H-quinolin-2-one 
• 792122-50-0 3-methyl-3-(3-methylamino-propyl)-1-p-tolyl-3,4-dihydro-1H-quinolin-2-one 
• 792122-33-9 3-methyl-3-(3-methylamino-propyl)-1-phenyl-3,4-dihydro-1H-quinolin-2-one 
• 868701-30-8 3-(3-hydroxy-propyl)-1-(4-methoxy-benzyl)-3-methyl-3,4-dihydro-1H-quinolin-2-one 

Relevant academic research and scientific papers

1-Aryl-3,4-dihydro-1H-quinolin-2-one derivatives, novel and selective norepinephrine reuptake inhibitors

A novel series of 1-aryl-3,4-dihydro-1H-quinolin-2-ones have been discovered as potent and selective norepinephrine reuptake inhibitors. Efficient synthetic routes have been developed which allow for the multi-gram preparation of both final targets and ad

TREATMENT OF LEARNING DISABILITIES AND MOTOR SKILLS DISORDER WITH NOREPINEPHRINE REUPTAKE INHIBITORS

Provided are methods and medicaments for treating a learning disability or a Motor Skills Disorder, comprising administering to a patient in need of such treatment an effective amount of a selective norepinephrine reuptake inhibitor.

TREATMENT OF PERVASIVE DEVELOPMENTAL DISORDERS WITH NOREPINEPHRINE REUPTAKE INHIBITORS

Provided are methods and medicaments for treating a Pervasive Developmental Disorder, comprising administering to a patient in need of such treatment an effective amount of a selective norepinephrine reuptake inhibitor.

TREATMENT OF HOT FLASHES, IMPULSE CONTROL DISORDERS AND PERSONALITY CHANGE DUE TO A GENERAL MEDICAL CONDITION

Selective norepinephrine reuptake inhibitors are useful for the prevention or treatment of hot flashes, vasomotor symptoms, impulse control disorders or personality change due to a general medical condition.

QUINOLONE DERIVATIVES

This invention relates to compounds of formula (I) where -X-, n, R1, R3 and Ar- have the values defined herein, their preparation and use as norepinephrine reuptake inhibitors useful for the treatment of nervous system disorders