79225-79-9

Upstream product

• 1147550-11-5 ammonium thiocyanate 
• 98-88-4 benzoyl chloride 
• 26907-54-0 2-amino-5-(4-methylphenyl)-1,3,4-thiadiazole 
• 532-55-8 Benzoyl isothiocyanate 
• 1079-82-9 1-(p-methylbenzoyl)-3-thisemicarbazide 

Downstream Products

• 79225-95-9 5-Phenyl-2-p-tolyl-[1,3,4]thiadiazolo[3,2-a][1,3,5]triazine-7-thione 
• 120450-58-0 6-benzoylimino-2-p-tolyl-1,3,4-thiadiazolo-<3,2-b><1,2,4>thiadiazoline 

Relevant academic research and scientific papers

Synthesis of 6-Aroylimino-2-aryl-1,3,4-thiadiazolothiadiazolines

Reaction of 2-amino-5-aryl-1,3,4-thiadiazoles (V) with aroyl isothiocyanates gives 2-aroylamino-5-aryl-1,3,4-thiadiazoles (VII) and N-aroyl-N'-(5-aryl-1,3,4-thiadiazol-2-yl)thioureas (VIII).Contrary to earlier reports, cyclisation of VIII in the presence of PCl5 in POCl3 yields 6-aroylimino-2-aryl-1,3,4-thiadiazolo-thiadiazolines (X).Cyclisation of VIII in the presence of other oxidising agents also leads to X.

Synthesis and Antifungal Activity of Some 1,3,4-Thiadiazolo-s-triazine-7-thiones and N-Acyl-N'-(5-aralkyl/aryl-1,3,4-thiadiazol-2-yl)thioureas

1-Acylthiosemicarbazides (1) on cyclodehydration with conc.H2SO4 give the corresponding 2-amino-5-aralkyl/aryl-1,3,4-thiadiazoles (2) which on treatment with acyl chlorides and NH4SCN in acetone followed by cyclisation of the resultant N-acyl-N'-(5-aralky