79226-30-5

Upstream product

• 79226-08-7 4-hydroxy-5,8-dimethoxy-2-thio-2H-1-benzopyran 
• 79226-09-8 2-ethylthio-5,8-dimethoxy-4H-1-benzopyran-4-one 
• 52099-27-1 3,6-dimethoxy-2-hydroxyacetophenone 
• 344263-81-6 2-ethylsulphinyl-5,8-dimethoxy-4H-1-benzopyran-4-one 
• 108-95-2 phenol 

Relevant academic research and scientific papers

Synthesis of 2-Aminochromones. Studies on the Nucleophilic Displacement of Sulphinyl and Sulphonyl Groups in the 2-Position of 5,8-Dimethoxychromone

The synthesis is described of a number of N-substituted 2-amino-5,8-dimethoxychromones (1) by replacement of the sulphoxide group in 2-ethylsulphinyl-5,8-dimethoxychromone (5a) with the appropriate amine.Analogous substitution of 2-ethylsulphonyl-5,8-dimethoxychromone (5b) is also possible but limited by the instability of the sulphone.Replacement reactions of 5a involving oxygen, sulphur, and phosphorus nucleophiles are also described.