79233-65-1Relevant articles and documents
Ureido-based peptidomimetic inhibitors of herpes simplex virus ribonucleotide reductase: An investigation of inhibitor bioactive conformation
Moss, Neil,Beaulieu, Pierre,Duceppe, Jean-Simon,Ferland, Jean-Marie,Gauthier, Jean,Ghiro, Elise,Goulet, Sylvie,Guse, Ingrid,Llinàs-Brunet, Montse,Plante, Raymond,Plamondon, Louis,Wernic, Dominik,Déziel, Robert
, p. 2178 - 2187 (2007/10/03)
We have been investigating peptidomimetic inhibitors of herpes simplex virus (HSV) ribonucleotide reductase (RR). These inhibitors bind to the HSV RR large subunit and consequently prevent subunit association and subsequent enzymatic activity. This report