79234-11-0

Upstream product

• 61-54-1 tryptamine 
• 765-87-7 cyclohexane-1,2-dione 

Downstream Products

• 79234-25-6 1,3,4,9a-tetrahydro-2-oxo-N,N'-diphenyl-1,4-ethano-3,4a-(iminoethano)-4aH-carbazole-9,12(2H)-dicarboxamide oxime 
• 79234-26-7 1,3,4,9a-tetrahydro-2-hydroxy-N,N'-diphenyl-1,4-ethano-3,4a-(iminoethano)-4aH-carbazole-9,12-(2H)-dicarboxamide 
• 79234-18-7 N,N'-dicyclohexyl-1,3,4,9a-tetrahydro-2-oxo-1,4-ethano-3,4a-(iminoethano)-4aH-carbazole-9,12(2H)-dicarboxamide 
• 79234-24-5 3,3a,4,4a,10,10a-hexahydro-3a-hydroxy-2-oxo-N,3-diphenyl-1,9b:4,10-diethanoimidazo<4,5-b>carbazole-5(2H)-carboxamide 
• 79234-19-8 1,3,4,9a-tetrahydro-2-oxo-N,N'-diphenyl-1,4-ethano-3,4a-(iminoethano)-4aH-carbazole-9,12(2H)-dicarboxamide 
• 79234-23-4 N,3-dicyclohexyl-3,3a,4,4a,10,10a-hexahydro-3a-hydroxy-2-oxo-1,9b:4,10-diethanoimidazo<4,5-b>carbazole-5(2H)-carboxamide 

Relevant academic research and scientific papers

2',3',4',9'-Tetrahydrospiroindol>-2-ones and Their Transformations into 2,3,4,4a,5,6,9,14-Octahydro-4a-hydroxy-1H,8H-pyridodiindole-5-carbonitriles and 5-Substituted 2,3,4,4a,9,14-hexahydro-4a-hydroxy-1H,8H-indolopyrido<1,2-c...

The condensation of 1H-indol-3-ethanamine derivatives 1 with 1,2-cyclohexanedione (2) and subsequent transformation of the resulting 2-imino>cyclohexanones (3) into 2',3',4',9'-tetrahydrospiroindol>-2-ones 4 using Pistet-Spengler (1) reaction conditions is described.The reaction of 4 with acrylonitrile gave a mixture of pentacyclic derivatives, 2,3,4,4a,5,6,9,14-octahydro-4a-hydroxy-1H,8H-pyridodiindole-5-carbonitriles 12.Treatment of 4 with alkyl and aryl isocyanates (14) at room temperature gave 5-sub stituted-2,3,4,4a,9,14-hexahydro-4a-hydroxy-1H,8H-indolopyridobenzimidazol-6-(5H)ones 16.Dehydration of 16 gave 5-substituted-2,3,9,14-tetrahydro-1H,8H-indolopyridobenzimidazol-6-(5H)ones (17).Spectral and chemical evidence is presented to confirm structures 4,12,16, and 17.