79234-23-4

Upstream product

• 94956-80-6 N-cyclohexyl-1,2,3,4,9,9a-hexahydro-2-oxo-1,4-ethano-3,4a-(iminoethano)-4aH-carbazole-12-carboxamide 
• 79234-11-0 2-<<2-(1H-indol-3-yl)ethyl>imino>cyclohexanone 
• 3173-53-3 Cyclohexyl isocyanate 
• 94956-82-8 3-cyclohexyl-3a,4,4a,5,10,10a-hexahydro-3a-hydroxy-1,9b:4,10-diethanoimidazo<4,5-b>carbazol-2(3H)-one 
• 79234-12-1 3,4,9,9a-tetrahydro-1,4-ethano-3,4a-(iminoethano)-4aH-carbazol-2(1H)-one 
• 79234-18-7 N,N'-dicyclohexyl-1,3,4,9a-tetrahydro-2-oxo-1,4-ethano-3,4a-(iminoethano)-4aH-carbazole-9,12(2H)-dicarboxamide 

Relevant academic research and scientific papers

3,4,9,9a-Tetrahydro-1,4-ethano-3,4a-(iminoethano)-4aH-carbazol-2(1H)-one Derivatives. 2. Unusual Results from Eschweiler-Clarke Methylation

The N-methylation of 3,4,9,9a-tetrahydro-1,4-ethano-3,4a-(iminoethano)-4aH-carbazol-2(1H)-one (1) under Eschweiler-Clarke reaction conditions using excess formaldehyde gave 3,4,9,9a-tetrahydro-6,8,9,12-tetramethyl-1,4-ethano-3,4a-(iminoethano)-4aH-carbazol-2(1H)-one (1b).When an equivalent amount of formaldehyde was used, the main products were 3,4,9,9a-tetrahydro-12-methyl-1,4-ethano-3,4a-(iminoethano)-4aH-carbazol-2(1H)-one (1c) and 1,3,4,9a-tetrahydro-12-methyl-1,4-ethano-3,4a-(iminoethano)-4aH-carbazole-9(2H)-carboxaldehyde (1d).

3,4,9,9a-Tetrahydro-1,4-ethano-3,4a-(iminoethano)-4aH-carbazol-2(1H)-one Derivatives and N,3-Disubstituted 3,3a,4,4a,10,10a-Hexahydro-3a-hydroxy-2-oxo-1,9b:4,10-diethanoimidazocarbazole-5(2H)-carboxamides

The treatment of 2-imino>cyclohexanone (1) with hot concentrated sulfuric acid to give the pentacyclic compound 4 is described.The treatment of 4 with 2 equiv of isocyanate gave N,3-disubstituted 3,3a,4,4a,10,10a-hexahydro-3a-hydroxy-2-oxo-1,9b:4,10-diethanoimidazocarbazole-5(2H)-carboxamides 11.When bulky isocyanates were used, the reaction stopped at the diurea stage 10.The latter were irreversibly converted to 11 by heating at 140 deg C.