79258-29-0Relevant academic research and scientific papers
THE 2-(METHYLTHIOMETHOXY)ETHOXYCARBONYL PROTECTING GROUP
Jones, Simon S.,Reese, Colin B.,Sibanda, Samson
, p. 1933 - 1936 (2007/10/02)
Alcohols (ROH) may be converted into their MTMEC derivatives (6) by acylation with 2-(methylthiomethoxy)ethoxycarbonyl chloride (5); the MTMEC "protected protecting group" may be removed by treatment first with Hg(II) perchlorate in the presence of 2,4,6-collidine or pyridine in aceton-water solution, followed by hydrolysis under very mild basic conditions.
