79258-44-9Relevant academic research and scientific papers
DEALKYLATION OF NUCLEOSIDE ARYLMETHYL 2-CHLOROPHENYL PHOSPHATES: THE 2,4-DINITROBENZYL PROTECTING GROUP
Christodoulou, Chris,Reese, Colin B.
, p. 951 - 954 (2007/10/02)
Following a study of the effect of benzyl substitution on the rates of nucleophilic dealkylation of phosphotriesters, 2,4-dinitrobenzyl is proposed as a temporary protecting group for 3'-terminal phosphodiester functions in oligonucleotide synthesis.
A General Approach to the Chemical Synthesis of Oligodeoxyribonucleotides
Balgobin, Neil,Josephson, Staffan,Chattopadhyaya, Jyoti B.
, p. 201 - 212 (2007/10/02)
A general procedure for the synthesis of oligodeoxynucleotides has been described using 9-phenylxanthen-9-yl as a 5'-protecting group.The building blocks 9 and 11, all sixteen of them in each category (Tables 2 and 3), have been unambiguously synthesized
