79263-00-6Relevant articles and documents
The Synthesis of 7,9-Dimethoxy-5,11-Dimethyl-6H-pyrido-Carbazole (7,9-Dimethoxyellipticine) via a Regioselective Bromination, and some Bromination and Ipso Substitution Reactions of the 2,4-Dimethoxycarbazole System
Hall, Robin J.,Shannon, Patrick V. R.,Oliveira-Campos, Ana M.-F.,Queiroz, Maria-Joao R. P.
, p. 114 - 156 (2007/10/02)
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Pyrazoloquinazolin-9-ones: A New Series of Antiallergic Agents
Sircar, Jagadish C.,Capiris, Thomas,Kesten, Stephen J.,Herzig, David J.
, p. 735 - 742 (2007/10/02)
A new series of antiallergic agents, pyrazoloquinazolin-9-ones, was synthesized and evaluated for inhibitory effects in the rat reaginic passive cutaneous anaphylaxis (PCA) screen.Several analogues were found to be more potent than cromolyn sodium intravenously.Structure-activity relationships are discussed.One of the compounds, 4,9-dihydro-5-methoxy-9-oxopyrazoloquinazoline-2-carboxylic acid (36), was found to be approximately 250 times more potent than cromolyn sodium intravenously.