76746-30-0Relevant academic research and scientific papers
TERTIARY AMIDES AND METHOD OF USE
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, (2017/11/04)
Compunds of Formula (I) and pharmaceutically acceptable salts thereof, wherein G1, G2, G3, L1, L2, and L3 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by the modulation of lysophosphatidic acid receptor 1. Methods for making the compounds are described. Also described are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
Development of benzo[1,4]oxazines as biofilm inhibitors and dispersal agents against Vibrio cholerae
Warner, Christopher J. A.,Cheng, Andrew T.,Yildiz, Fitnat H.,Linington, Roger G.
supporting information, p. 1305 - 1308 (2015/02/19)
Bacterial biofilms are estimated to be associated with over 65 percent of all nosocomial infections. However, no therapeutics have been approved by the FDA which directly mediate biofilm formation or persistence. Herein we report oxazine 25 as a highly po
A concise synthesis of enantiopure circumdatins E, H and J
Zhichkin, Paul E.,Jin, Xiaomin,Zhang, Honglu,Peterson, Lisa H.,Ramirez, Catherine,Snyder, Tara M.,Burton, Hilde S.
supporting information; experimental part, p. 1287 - 1289 (2010/06/17)
A concise total synthesis of enantiopure circumdatins E, H and J has been developed using a reductive cyclization of chiral N-prolinoyl-2-nitrobenzamides to construct the core quinazolinone ring.
Alkaloids from Annonaceae 93. First synthesis of a meta-disubstituted aporphine
Roblot, F.,Hocquemiller, R.,Cave, A.
, p. 258 - 267 (2007/10/02)
The synthesis of a new aporphinoid alkaloid, substituted on the 9 and 11 positions, is reported.An unexpected reactivity has been observed for several intermediates.It has been attributed to the position of the methoxy groups with regard to the nitro group.
