792923-01-4

Upstream product

• 501-53-1 benzyl chloroformate 
• 126809-69-6 2,4-dimethoxy-3-methyl-1-(methoxymethoxy)benzene 
• 792922-98-6 (2S,3R,4S)-4-Benzyloxycarbonylamino-2-[(R)-1-(3,5-dimethoxy-2-methoxymethoxy-4-methyl-phenyl)-allyl]-3-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 792923-00-3 (1R,2S,5S)-2-[(R)-1-(3,5-Dimethoxy-2-methoxymethoxy-4-methyl-phenyl)-2-hydroxy-ethyl]-3,6-diaza-bicyclo[3.1.0]hexane-3,6-dicarboxylic acid 6-benzyl ester 3-tert-butyl ester 
• 792922-99-7 (1R,2S,5S)-2-[(R)-1-(3,5-Dimethoxy-2-methoxymethoxy-4-methyl-phenyl)-allyl]-3,6-diaza-bicyclo[3.1.0]hexane-3,6-dicarboxylic acid 6-benzyl ester 3-tert-butyl ester 
• 792922-81-7 acetic acid 1-(3,5-dimethoxy-2-methoxymethoxy-4-methylphenyl)allyl ester 
• 792922-80-6 1-(3,5-dimethoxy-2-methoxymethoxy-4-methylphenyl)prop-2-en-1-ol 
• 5673-07-4 2,6-dimethoxytoluene 
• 7149-92-0 2,4-dimethoxy-3-methylbenzaldehyde 
• 19676-67-6 2,4-dimethoxy-3-methylphenol 

Downstream Products

• 792923-03-6 (1R,2S,5S)-2-[(R)-2-Carbamoyloxy-1-(5-methoxy-4-methyl-3,6-dioxo-cyclohexa-1,4-dienyl)-ethyl]-3,6-diaza-bicyclo[3.1.0]hexane-3,6-dicarboxylic acid dibenzyl ester 
• 792923-02-5 (1R,2S,5S)-2-[(R)-2-Carbamoyloxy-1-(3,5-dimethoxy-2-methoxymethoxy-4-methyl-phenyl)-ethyl]-3,6-diaza-bicyclo[3.1.0]hexane-3,6-dicarboxylic acid dibenzyl ester 

Relevant academic research and scientific papers

Mitomycin synthetic studies: Stereocontrolled and convergent synthesis of a fully elaborated aziridinomitosane

Full details of a stereocontrolled and convergent synthetic route to 9a-desmethoxymitomycin A (1) are reported. The target molecule possesses the parent tetrahydropyrrolo[1,2-a]indole ring system characteristic of the mitomycin family of antitumor agents.