792948-35-7

Upstream product

• 792948-33-5 (2S)-1-(3-benzyloxy-4-methyl-2-nitrobenzoyl)-4-vinyl-2,5-dihydro-1H-pyrrole-2-carboxylic acid methyl ester 
• 792948-19-7 (2S)-methyl 2-(((benzyloxy)carbonyl)(prop-2-yn-1-yl)amino)-4-(methylsulfinyl)butanoate 
• 792948-20-0 (S)-4-vinyl-2,5-dihydropyrrole-1,2-dicarboxylic acid 2-methyl ester 

Downstream Products

• 792948-37-9 (11aS)-3-(9-benzyloxy-8-methyl-5,11-dioxo-5,10,11,11a-tetrahydro-3H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-2-yl)acrylic acid ethyl ester 
• 792948-29-9 (11aS)-3-(9-benzyloxy-8-methyl-5,11-dioxo-5,10,11,11a-tetrahydro-1H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-2-yl)acrylic acid ethyl ester 
• 792948-31-3 C₂₅H₂₂N₂O₅ 
• 792948-25-5 (11aS)-3-(9-benzyloxy-8-methyl-5,11-dioxo-5,10,11,11a-tetrahydro-3H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-2-yl)acrylic acid methyl ester 
• 792948-34-6 (11aS,E)-acetic acid 3-(9-benzyloxy-8-methyl-5,11-dioxo-5,10,11,11a-tetrahydro-3H-benzo[e]pyrrolo[1,2-a][1,4]diazepin-2-yl)allyl ester 

Relevant academic research and scientific papers

Synthetic study of (+)-anthramycin using ring-closing enyne metathesis and cross-metathesis

Synthesis of (+)-anthramycin was examined. A pyrrolobenzodiazepine skeleton could be synthesized by reductive cyclization of pyrrolidine derivative, which was obtained by enyne metathesis. The conjugated enamide ester part of (+)-anthramycin derivative was constructed by cross-metathesis. Graphical Abstract.