79295-86-6Relevant academic research and scientific papers
Electrochemical 1,4-reduction of α,β-unsaturated ketones with methanol and ammonium chloride as hydrogen sources
Huang, Binbin,Li, Yanan,Yang, Chao,Xia, Wujiong
, p. 6731 - 6734 (2019/06/17)
A sustainable, chemoselective 1,4-reduction of α,β-unsaturated ketones by means of an electrochemical method is presented, wherein the extremely inexpensive ammonium chloride (NH4Cl) is applied as the only additive. The reaction proceeds smoothly in the air at ambient temperature. Mechanistic studies reveal that both NH4Cl and solvent methanol work as hydrogen donors.
Borylation and selective reduction of α,β-unsaturated ketones under mild conditions catalyzed by Cu nanoparticles
Zhou, Xin-Feng,Sun, Yu-Yang,Wu, Ya-Dong,Dai, Jian-Jun,Xu, Jun,Huang, Yu,Xu, Hua-Jian
, p. 5691 - 5698 (2016/08/23)
An effective strategy for synthesis of Cu nanoparticles is designed, these nanoparticles have high catalytic activity in conjugate addition of B2(pin)2and α,β-unsaturated ketones. The reaction of protodeboration can proceed with adding NaOtBu. In this way, a new method to reduce the conjugated alkenes of α,β-unsaturated ketones is developed with organoboranes as intermediates. Cu nanocrystals also have excellent performance in gram-scale reaction and recycling experiment. A possible mechanism is proposed.
