79312-41-7

Basic information

• Product Name: 2-Thiazolecarboxylic acid, 4,5-dimethyl-
• Synonyms: 2-Thiazolecarboxylic acid, 4,5-dimethyl-;4,5-Dimethylthiazole-2-carboxylic acid;Dimethyl-1,3-thiazole-2-carboxylic acid;4,5-Dimethyl-1,3-thiazole-2-carboxylicacid
• CAS NO: 79312-41-7
• Molecular Formula: C₆H₇NO₂S
• Molecular Weight: 157.19
• Mol File: 79312-41-7.mol

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 2-Thiazolecarboxylic acid, 4,5-dimethyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Thiazolecarboxylic acid, 4,5-dimethyl-(79312-41-7)
• EPA Substance Registry System: 2-Thiazolecarboxylic acid, 4,5-dimethyl-(79312-41-7)

Safety Data

• Hazardous Substances Data: 79312-41-7(Hazardous Substances Data)

Usage

Uses

Used in Pharmaceutical Industry:
2-Thiazolecarboxylic acid, 4,5-dimethyl-, is used as an intermediate in the synthesis of various pharmaceuticals for its potential biological activities, including antiviral, antibacterial, and antifungal properties. Its unique structure allows it to be a building block in the development of new drugs with therapeutic applications.
Used in Agrochemical Industry:
In the agrochemical sector, 2-Thiazolecarboxylic acid, 4,5-dimethyl-, is utilized as a key component in the synthesis of agrochemicals, contributing to the development of pesticides and other products that protect crops from diseases and pests, thereby enhancing agricultural productivity.
Used in Organic Synthesis:
2-Thiazolecarboxylic acid, 4,5-dimethyl-, serves as a versatile building block in organic synthesis, enabling the creation of a wide range of organic compounds with diverse applications across various industries, from pharmaceuticals to materials science. Its reactivity and structural features make it a preferred choice for chemists in designing and synthesizing novel molecules with specific functions and properties.

Upstream product

• 79247-96-4 4,5-dimethyl-thiazole-2-carboxylic acid ethyl ester 
• 3581-91-7 4,5-Dimethylthiazole 
• 124-38-9 carbon dioxide 

Downstream Products

• 3581-91-7 4,5-Dimethylthiazole 
• 15055-59-1 2-benzyl-4,5-dimethyl-thiazole 
• 28168-48-1 (4,5-dimethylthiazol-2-yl)(phenyl)methanone 
• 104830-58-2 3-ethyl-4,5-dimethylthiazolium picrate 

Relevant articles and documents

NOVEL CHIRAL N-ACYL-5,6,7,(8-SUBSTITUTED)-TETRAHYDRO-[1,2,4]TRIAZOLO[4,3-a]PYRAZINES AS SELECTIVE NK-3 RECEPTOR ANTAGONISTS, PHARMACEUTICAL COMPOSITION, METHODS FOR USE IN NK-3 RECEPTOR MEDIATED DISORDERS AND CHIRAL SYNTHESIS THEREOF

The present invention relates to novel compounds of Formula I and their use in therapeutic treatments. The invention further relates to a novel chiral synthesis of 5,6,7,(8-substituted)-tetrahydro-[1,2,4]triazolo[4,3-a]pyrazines using N-sp3 protective groups. The invention also provides intermediates for use in the synthesis of compounds of Formula I.

USE OF THIAZOLIUM-2-CARBOXYLATES TO INDUCE BENZOIN CONDENSATIONS

The preparation of 3-ethyl-4,5-dimethylthiazolium-2-carboxylate and its use to promote the benzoin condensation and the formoin reaction is described.

An Infrared Study of Rotational Isomerism in Thiazole-2-carboxylates

A series of alkyl thiazole-2-carboxylates containing a range of substituents at the 4- and 5-positions has been prepared.Solutions of these esters (mostly new compounds) show well resolved doublets in the i.r.C=O region which arise from rotational isomers.The higher wavenumber components are assigned to the more polar carbonyl O,S-anti-s-trans-rotamers and the lower wavenumber components to the carbonyl O,S-syn-s-trans-forms.Small, but systematic, differences between the methyl esters are noted.