79314-43-5

Basic information

• Product Name: N-(4-fluorophenethyl)benzamide
• Synonyms: N-(4-fluorophenethyl)benzamide
• CAS NO: 79314-43-5
• Molecular Weight: 243.281
• Mol File: 79314-43-5.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: N-(4-fluorophenethyl)benzamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(4-fluorophenethyl)benzamide(79314-43-5)
• EPA Substance Registry System: N-(4-fluorophenethyl)benzamide(79314-43-5)

Safety Data

• Hazardous Substances Data: 79314-43-5(Hazardous Substances Data)

Upstream product

• 91344-86-4 3-methoxy-3-oxoprop-1-en-1-yl benzoate 
• 1583-88-6 4-fluoro-2-phenethylamine 
• 65-85-0 benzoic acid 

Downstream Products

• 1085542-21-7 1-phenyl-7-fluoro-3,4-dihydroisoquinoline 

Relevant articles and documents

Direct Amidation of Carboxylic Acids through an Active α-Acyl Enol Ester Intermediate

The development of a highly efficient and simple protocol for the direct amidation of carboxylic acids is described employing ynoates as novel coupling reagents. The transformation proceeds in good to excellent yields via in situ α-acyl enol ester intermediates formation under mild reaction conditions. This useful method has been demonstrated for a range of substrates to provide a succinct access to structurally diverse amides, including key intermediates of glibenclamide, tiapride hydrochloride, and nateglinide, and can be conducted on a mole scale.