79314-59-3Relevant academic research and scientific papers
Direct, practical, and powerful crossed aldol additions between ketones and ketones or aldehydes utilizing environmentally benign TiCl4-Bu3N reagent
Tanabe, Yoo,Matsumoto, Noriaki,Higashi, Takahiro,Misaki, Tomonori,Itoh, Tomotaka,Yamamoto, Misako,Mitarai, Kumi,Nishii, Yoshinori
, p. 8269 - 8280 (2007/10/03)
An efficient TiCl4-Bu3N - (cat. TMSCl)-promoted aldol addition between ketones and ketones or aldehydes was performed. This environmentally benign method is advantageous from a green chemical viewpoint with regard to yield, substrate
Catalytic TMSCl promoted powerful aldol addition and Claisen condensation mediated by TiCl4/Bu3N agent: Comparison and evaluation with the Mukaiyama aldol addition
Yoshida, Yoshihiro,Matsumoto, Noriaki,Hamasaki, Ryota,Tanabe, Yoo
, p. 4227 - 4230 (2007/10/03)
TMSCl catalyst (0.05 equiv) significantly promoted the TiCl4/Bu3N-mediated direct cross aldol additions of sterically crowded ketones and α-hetero substituted ketones, and also the direct Claisen condensation between methyl esters.
Lanthanide Ion Assisted Electrochemically Initiated Aldol Condensations
Fry, Albert J.,Susla, Marko,Weltz, Michael
, p. 2496 - 2498 (2007/10/02)
An electrochemical process for effecting directed aldol condensation is described.It is carried out under neutral conditions, can tolerate a wide variety of functional groups, is highly selective for aldehydes over ketones, requires only simple apparatus, and depends for its success upon the efficient mediating effect of trivalent lanthanide ions.
