79349-38-5Relevant academic research and scientific papers
Norbornadienes: Robust and Scalable Building Blocks for Cascade "click" Coupling of High Molecular Weight Polymers
St Amant, Andre H.,Discekici, Emre H.,Bailey, Sophia J.,Zayas, Manuel S.,Song, Jung-Ah,Shankel, Shelby L.,Nguyen, Shay N.,Bates, Morgan W.,Anastasaki, Athina,Hawker, Craig J.,De Alaniz, Javier Read
, p. 13619 - 13624 (2019)
Herein, we report the development of a scalable and synthetically robust building block based on norbornadiene (NBD) that can be broadly incorporated into a variety of macromolecular architectures using traditional living polymerization techniques. By tak
Synthesis of photoresponsive hybrid alginate hydrogel with photo-controlled release behavior
Chiang, Chien-Ying,Chu, Chih-Chien
, p. 18 - 25 (2015)
A photoresponsive hybrid alginate hydrogel was successfully prepared by Ca2+-mediated crosslinking reaction with a mixture of β-cyclodextrin-grafted alginate (β-CD-Alg) and diazobenzene-modified poly(ethylene glycol) (Az2-PEG). The w
The selective synthesis ofN-arylbenzene-1,2-diamines or 1-arylbenzimidazoles by irradiating 4-methoxy-4′-substituted-azobenzenes in different solvents
Chen, Po-Yi,Hsu, Chi-Wei,Ho, Tong-Ing,Ho, Jinn-Hsuan
, p. 6662 - 6666 (2021/02/21)
The solvent-controllable photoreaction of 4-methoxyazobenzenes to afford 1-aryl-1H-benzimidazoles orN-arylbenzene-1,2-diamines has been studied. The irradiation of 4-methoxyazobenzenes in DMF containing 0.5 M hydrochloric acid providedN2-aryl-4-methoxybenzene-1,2-diamines as the major product, while irradiation in acetal containing 0.16 M hydrochloric acid led to 1-aryl-6-methoxy-2-methyl-1H-benzimidazoles as the major product. A possible reaction mechanism explaining the selectivity was also discussed.
Receptor with an active methylene group as binding site for extraction of inorganic fluoride ions from seawater
Madhuprasad,Trivedi, Darshak R.
, p. 1001 - 1008 (2014/08/05)
Two new receptors R1 and R2 based on triphenylphosphonium salts with an active methylene group as binding site have been designed and synthesised for the detection of F- ions. The detection limit of these receptors in organic media was found to
Mannich bases of phenolic azobenzenes possessing cytotoxic activity
Dimmock,Erciyas,Kumar,Hetherington,Quail,Pugazhenthi,Arpin,Hayes,Allen,Halleran,De Clercq,Balzarini,Stables
, p. 583 - 594 (2007/10/03)
A number of arylazophenols 1 were converted into the corresponding mono Mannich bases 2 from which two quaternary salts 3a,b and an ester 3c were prepared. A series of bis Mannich bases 4 were also synthesized. The angles (φ) made between one of the aryl rings and the adjacent azo linkage were determined by electronic absorption spectroscopy. X-ray crystallographic data were obtained for some of the Mannich bases. The compounds were evaluated against murine P388 D1 and L1210 cells and two human T-lymphocyte (Molt 4, CEM) lines, and most of the derivatives were also screened against a panel of human tumour cell lines. A number of correlations were noted between cytotoxicity and various physicochemical constants as well as some structural features determined by X-ray crystallography. Several of the Mannich bases were shown to have mutagenic properties using the λ RK mutatest; the compounds in series 2 and 4 have the ability to penetrate the central nervous system, as revealed by their anticonvulsant properties. While series 2-4 have the potential to deaminate forming ortho quinone methides which would be capable of alkylating cellular thiols, the results of stability studies suggest that the bioactivities noted were due to the molecules per se.
