79360-94-4

Usage

Uses

Used in Flavoring Industry:
Ethyl 4,4-difluoro-5-hydroxypentanoate is used as a flavoring agent in food and beverages, providing a fruity aroma and enhancing the taste of products.
Used in Pharmaceutical Industry:
Ethyl 4,4-difluoro-5-hydroxypentanoate is used in the production of pharmaceuticals, contributing to the development of new drugs and improving the efficacy of existing medications.
Used in Agrochemical Industry:
Ethyl 4,4-difluoro-5-hydroxypentanoate is utilized in the formulation of agrochemicals, such as pesticides and herbicides, to increase their effectiveness and reduce environmental impact.
Used in Other Industrial Applications:
Ethyl 4,4-difluoro-5-hydroxypentanoate is employed in various other industries, such as cosmetics, fragrances, and coatings, due to its unique properties and versatility.

Upstream product

• 667-27-6 Ethyl bromodifluoroacetate 
• 140-88-5 ethyl acrylate 
• 428-97-7 2,2-difluoroglutaric acid diethyl ester 

Downstream Products

• 911635-43-3 3-t-butoxycarbonylamino-4-(5,5-difluoro-2-oxo-piperidin-1-yl)butyric acid 

Relevant academic research and scientific papers

Skipped Fluorination Motifs: Synthesis of Building Blocks and Comparison of Lipophilicity Trends with Vicinal and Isolated Fluorination Motifs

Given there is an optimal lipophilicity range for orally bioavailable drugs, structural modifications applied in the drug development process are not only focused on optimizing bioactivity but also on fine-tuning lipophilicity. Fluorine introduction can b

TREATMENT OF RESPIRATORY DISEASES WITH AMINO ACID COMPOUNDS

The invention relates to methods of therapy using compounds of formula (I) and formula (II): or a salt thereof, wherein R1, R2, R10, R11, R12, R13, R14, R15, R16, q and p are as described herein. Compounds of formula (II) and pharmaceutical compositions thereof are integrin inhibitors that are useful in therapy for a condition, for example, caused by or associated with an infectious agent, shock, pancreatitis, or trauma. The condition can include one or more of pulmonary fibrosis associated with rheumatoid arthritis or progressive familial intrahepatic cholestasis (PFIC).

DOSAGE FORMS AND REGIMENS FOR AMINO ACID COMPOUNDS

The invention relates to dosage forms for daily administration of compounds of formula (A) and formula (I): or a salt thereof, wherein R1, R2, R10, R11, R12, R13, R14, R15, R16, q and p are as described herein. Compounds of formula (A), formula (I), and pharmaceutical compositions thereof are ανβ6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP),

AMINO ACID COMPOUNDS AND METHODS OF USE

The invention relates to compounds of formula (A) and formula (I): or a salt thereof, wherein R1, R2, R10, R11, R12, R13, R14, R15, R16, q and p are as described herein. Compounds of formula (A), formula (I), and pharmaceutical compositions thereof are αvβ6 integrin inhibitors that are useful for treating fibrosis such as idiopathic pulmonary fibrosis (IPF) and nonspecific interstitial pneumonia (NSIP).

PRODUCTION METHOD OF INTERMEDIATE COMPOUND FOR SYNTHESIZING MEDICAMENT

The present invention relates to a novel method for preparing a compound of formula (2) as the intermediate, which can be effectively used for preparation of a compound of formula (1) exhibiting good inhibitory activity against dipeptidyl peptidase IV enz

PRODUCTION METHOD OF INTERMEDIATE COMPOUND FOR SYNTHESIZING MEDICAMENT

The present invention relates to a novel method for preparing a compound of formula (2) as the intermediate, which can be effectively used for preparation of a compound of formula (1) exhibiting good inhibitory activity against dipeptidyl peptidase IV enz

Certain fluorine substituted PGI2 compounds

Prostaglandin and prostacyclin compounds which are fluorine substituted in any one or more of the following positions, 4,4; 7,7; 10,10; and 5.