793669-75-7

Basic information

• Product Name: 2-Undecene-1,6-dione, 1-phenyl-, (2E)-
• CAS NO: 793669-75-7
• Molecular Formula: C17H22O2
• Molecular Weight: 258.36
• Mol File: 793669-75-7.mol

Chemical Properties

• CAS DataBase Reference: 2-Undecene-1,6-dione, 1-phenyl-, (2E)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Undecene-1,6-dione, 1-phenyl-, (2E)-(793669-75-7)
• EPA Substance Registry System: 2-Undecene-1,6-dione, 1-phenyl-, (2E)-(793669-75-7)

Safety Data

• Hazardous Substances Data: 793669-75-7(Hazardous Substances Data)

Upstream product

• 74327-29-0 4-oxo-nonanal 
• 98-86-2 acetophenone 
• 107841-11-2 1-hydroxynonan-4-one 

Relevant articles and documents

Structure-activity relationship of anti-malarial spongean peroxides having a 3-methoxy-1,2-dioxane structure

In order to study the structure-activity relationship of anti-malarial spongean peroxides, several analogues concerning with the 6-methoxyacetyl moiety and the 3-pentyl residue in methyl 2-(3-methoxy-3-pentyl-1,2-dioxan-6-yl) acetate were synthesized and evaluated for anti-malarial activity. In order to study the structure-activity relationship of anti-malarial spongean peroxides, several analogues concerning with the 6-methoxyacetyl moiety and the 3-pentyl residue in methyl 2-(3-methoxy-3-pentyl-1,2-dioxan-6-yl)acetate were synthesized and evaluated for anti-malarial activity. The tert-butyl ester analogue 14 showed stability in mouse serum and a high selectivity index against the malaria parasite, Plasmodium falciparum, and the citronellyl analogue 31 exhibited the strongest in vitro anti-malarial activity among them, and the imidazole analogue 25 showed desirable in vivo anti-malarial activity against P. berghei infected mice.