79379-66-1

Basic information

• Product Name: 2(5H)-Furanone, 5-ethoxy-3,4-diphenyl-
• CAS NO: 79379-66-1
• Molecular Formula: C18H16O3
• Molecular Weight: 280.323
• Mol File: 79379-66-1.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: 2(5H)-Furanone, 5-ethoxy-3,4-diphenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 2(5H)-Furanone, 5-ethoxy-3,4-diphenyl-(79379-66-1)
• EPA Substance Registry System: 2(5H)-Furanone, 5-ethoxy-3,4-diphenyl-(79379-66-1)

Safety Data

• Hazardous Substances Data: 79379-66-1(Hazardous Substances Data)

Usage

Structure

Furanone derivative with two phenyl groups and an ethoxy group attached to the furan ring

Usage

Synthesis of pharmaceuticals and found in some natural products

Biological activities

Antimicrobial and anti-inflammatory properties

Potential applications

Organic synthesis and medicinal chemistry

Upstream product

• 64-17-5 ethanol 
• 201230-82-2 carbon monoxide 
• 501-65-5 diphenyl acetylene 
• 74-85-1 ethene 

Relevant articles and documents

Silver-catalyzed ring-opening [3+2] annulation of cyclopropenones with amides

A ring-opening [3+2] annulation reaction between cyclopropenones and amides was developed to produce 5-amino-2-furanones. Insertion of the carbonyl group of an amide to the C-C single bond of a cyclopropenone occurred efficiently in the presence of a catalytic amount of silver(i) triflate.

RHODIUM CARBONYL-CATALYZED CARBONYLATION OF ACETYLENES IN ALCOHOL. SYNTHESIS OF 5-ALKOXY-2(5H)-FURANONES.

Reactions of internal acetylenes with CO in alcohols gave 5-alkoxy-3,4-disubstituted-2(5H)-furanones in good yields in the presence of rhodium catalysts containing basic alkali metal salts, e.g., Rh4(CO)12 or RhCl2*3H2O in combination with sodium carbonat