79390-76-4Relevant academic research and scientific papers
An EPR Study of a Model System for the Initial Oxygen Activation Process Caused by Adriamycin-Iron System
Tachibana, Masahiko,Tero-Kubota, Shozo,Iwaizumi, Masamoto
, p. 933 - 936 (2007/10/02)
1,4-Dihydroxyanthraquinone, a model compound for Adriamycin, is reduced by Fe2+-ADP complex to generate semiquinone, while by Fe2+-phosphate complex to hydroquinone.The difference is explained in terms of the higher redox potential of the latter reducing agent.Similar reduction reactions were observed in the case of the drug.
