79402-29-2Relevant academic research and scientific papers
EFFICIENT SYNTHESYS OF 2-VINYLCYCLOBUTANONES BY THE REARRANGEMENT OF 1-METHOXY-1-CYCLOPROPYLCARBINOLS UNDER NEUTRAL CONDITIONS
Cohen, Theodore,Brockunier, Linda
, p. 2917 - 2924 (2007/10/02)
A common synthesis of cyclobutanones involves the rearrangement of 1-alkoxy- or 1-(phenylthio)cyclopropylcarbinols under acidic conditions.We report that the synthetically useful 2-vinylcyclobutanones can be prepared in good yield in the absence of proton
PRACTICAL METHOD FOR USING ALKOXIDE-ACCELERATED VINYLCYCLOBUTANE RING EXPANSIONS IN THE SYNTHESIS OF SIX-MEMBERED RINGS. UNEXPECTED ORBITAL SYMMETRY ALLOWED AND FORBIDDEN 1,3-SIGMATROPIC REARRANGEMENTS.
Cohen,Bhupathy,Matz
, p. 520 - 525 (2007/10/02)
A practical method for utilizing the ring expansion of 2-vinylcyclobutanols to cyclohex-3-en-1-ols, even in cases in which very acid-sensitive groups are present, consists of the addition of 1-lithio- 1-methoxycyclopropanes to conjucated enals, brief trea
A SYNTHESIS OF 2-VINYLCYCLOBUTANONES USING 1-METHOXYCYCLOPROYLLITHIUM REAGENTS
Cohen, Theodore,Matz, James R.
, p. 2455 - 2458 (2007/10/02)
A facile synthesis of 2-vinylcyclobutanones consists of reductive lithiation of 1-phenylthio-1-methoxycyclopropanes, addition of enals or enones to the resulting α-lithioethers, and acid catalyzed rearrangement of the allylic alcohols thus produced.
