79412-71-8

Upstream product

• 19924-43-7 3-methoxyphenylacetonitrile 
• 2969-81-5 Ethyl 4-bromobutyrate 
• 79412-70-7 ethyl 5-cyano-5-(3-methoxyphenyl)pentanoate 
• 84555-01-1 ethyl 5-amino-5-(3-methoxyphenyl)pentanoate 

Downstream Products

• 84555-02-2 3-(3-Methoxy-phenyl)-1-propyl-azepane 
• 84554-93-8 6-(3-Methoxy-phenyl)-azepan-2-one 
• 79412-74-1 3-(3-methoxyphenyl)perhydroazepine 
• 79412-72-9 6-Amino-5-(3-methoxy-phenyl)-hexanoic acid; hydrochloride 

Relevant academic research and scientific papers

Synthesis and SAR Studies of Isoquinoline and Tetrahydroisoquinoline Derivatives as Melatonin Receptor Ligands

In our constant search for new successors of agomelatine, we report herein a new series of compounds resulting from bioisosteric modulation of the naphthalene ring. The isoquinoline and tetrahydroisoquinoline derivatives were synthesized and pharmacologic

New isoquinoline compounds

The invention relatests compound of formula (I): wherein: n is 1, 2 or 3, A represents a group X represents N or NR1, R2 represents an alkoxy, cycloalkyloxy or cycloalkylalkyloxy group. and medicinal products containing the same which are useful in treading or in preventing melatoninergic disorder.