79412-84-3

Basic information

• Product Name: 1-[3-(3-Amino-phenyl)-piperidin-1-yl]-propan-1-one
• Synonyms: 1-[3-(3-Amino-phenyl)-piperidin-1-yl]-propan-1-one
• CAS NO: 79412-84-3
• Molecular Weight: 232.326
• Mol File: 79412-84-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-[3-(3-Amino-phenyl)-piperidin-1-yl]-propan-1-one(CAS DataBase Reference)
• NIST Chemistry Reference: 1-[3-(3-Amino-phenyl)-piperidin-1-yl]-propan-1-one(79412-84-3)
• EPA Substance Registry System: 1-[3-(3-Amino-phenyl)-piperidin-1-yl]-propan-1-one(79412-84-3)

Safety Data

• Hazardous Substances Data: 79412-84-3(Hazardous Substances Data)

Upstream product

• 28987-79-3 m-tolylmagnesium bromide 
• 343966-00-7 3-<3-(methoxycarbonyl)phenyl>piperidine 
• 79412-82-1 1-[3-(3-Isocyanato-phenyl)-piperidin-1-yl]-propan-1-one 
• 79412-67-2 3-<3-(methoxycarbonyl)phenyl>-N-propionylpiperidine 
• 79601-28-8 3-(1-Propionylpiperidino-3-yl)-benzoic acid 
• 4385-77-7 3-(pyridine-3-yl)benzoic acid 
• 79601-27-7 3-pyridin-3-yl-benzoic acid methyl ester 
• 4385-67-5 3-(3-methylphenyl)pyridine 
• 626-55-1 3-Bromopyridine 
• 79412-83-2 [3-(1-Propionyl-piperidin-3-yl)-phenyl]-carbamic acid benzyl ester 

Downstream Products

• 79601-43-7 3-(3-aminophenyl)-N-n-propylpiperidine 

Relevant articles and documents

3-Phenylpiperidines. Central Dopamine-Autoreceptor Stimulating Activity

Thirty compounds related to the selective dopamine-autoreceptor agonist 3-(3-hydroxyphenyl)-N-n-propylpiperidine have been synthesized and tested for central dopamine-autoreceptor stimulating activity.The 3-(3-hydroxyphenyl)piperidine moiety seems indispensable for high potency and selectivity.Introduction of an additional hydroxyl group into the 4-position of the aromatic ring gives a compound with dopaminergic activity but lacking selectivity for autoreceptors. 3-(3-Hydroxyphenyl)-N-n-propylpyrrolidine, 3-(3-hydroxy)-N-n-propylperhydroazepine, and 3-(3-hydroxyphenyl)quinuclidine were all inactive.The most potent compounds were the N-isopropyl-, N-n-butyl-, N-n-pentyl-, and N-phenethyl-substituted 3-(3-hydroxyphenyl)piperidine derivatives.None of the compounds investigated seemed to have central noradrenaline- or serotonin-receptor stimulating activity.