79601-28-8

Upstream product

• 79412-67-2 3-<3-(methoxycarbonyl)phenyl>-N-propionylpiperidine 
• 626-55-1 3-Bromopyridine 
• 4385-67-5 3-(3-methylphenyl)pyridine 
• 79601-27-7 3-pyridin-3-yl-benzoic acid methyl ester 
• 4385-77-7 3-(pyridine-3-yl)benzoic acid 
• 343966-00-7 3-<3-(methoxycarbonyl)phenyl>piperidine 
• 28987-79-3 m-tolylmagnesium bromide 

Downstream Products

• 79601-43-7 3-(3-aminophenyl)-N-n-propylpiperidine 
• 79412-83-2 [3-(1-Propionyl-piperidin-3-yl)-phenyl]-carbamic acid benzyl ester 
• 79412-82-1 1-[3-(3-Isocyanato-phenyl)-piperidin-1-yl]-propan-1-one 
• 79412-84-3 1-[3-(3-Amino-phenyl)-piperidin-1-yl]-propan-1-one 

Relevant academic research and scientific papers

PHENYL-AZACYKLOALKANES

Compound of the formula STR1 wherein n is 1 or 2, Y is OH, R 1 COO--, R 2 R 3 NCOO--or R 4 O whereby R 1 is an alkyl group, or a possibly substituted phenyl group, R 2 is an alkyl, phenethyl, or benzyl or phenyl group, R 3 is H or an alkyl group and R 4 i

PHENYL-AZACYCLOALKANES AND USE THEREOF IN TREATMENT OF CENTRAL NERVOUS SYSTEM DISORDERS

Compound of the formula STR1 wherein n is 1 or 2, Y is OH, R 1 COO--, R 2 R 3 NCOO--or R 4 O whereby R 1 is an alkyl group, or a possibly substituted phenyl group, R 2 is an alkyl, phenethyl, or benzyl or phenyl group, R 3 is H or an alkyl group and R 4 i

SUBSTITUTED PHENYL PIPERIDINES

Compounds of the formula wherein n is 1 or 2, Y is OH, R1COO-,R2R3NCOO-or R4O whereby R1 is an alkyl group, or a possibly substituted phenyl group, R2 is an alkyl, phenethyl,benzyl or phenyl group, R3 is H or an alkyl group and R4 is an allyl or benzyl gr

3-Phenylpiperidines. Central Dopamine-Autoreceptor Stimulating Activity

Thirty compounds related to the selective dopamine-autoreceptor agonist 3-(3-hydroxyphenyl)-N-n-propylpiperidine have been synthesized and tested for central dopamine-autoreceptor stimulating activity.The 3-(3-hydroxyphenyl)piperidine moiety seems indispensable for high potency and selectivity.Introduction of an additional hydroxyl group into the 4-position of the aromatic ring gives a compound with dopaminergic activity but lacking selectivity for autoreceptors. 3-(3-Hydroxyphenyl)-N-n-propylpyrrolidine, 3-(3-hydroxy)-N-n-propylperhydroazepine, and 3-(3-hydroxyphenyl)quinuclidine were all inactive.The most potent compounds were the N-isopropyl-, N-n-butyl-, N-n-pentyl-, and N-phenethyl-substituted 3-(3-hydroxyphenyl)piperidine derivatives.None of the compounds investigated seemed to have central noradrenaline- or serotonin-receptor stimulating activity.