79455-23-5

Basic information

• Product Name: trans-cyclobutane-dicarbanilide-(1.2)
• CAS NO: 79455-23-5
• Molecular Weight: 294.353
• Mol File: 79455-23-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: trans-cyclobutane-dicarbanilide-(1.2)(CAS DataBase Reference)
• NIST Chemistry Reference: trans-cyclobutane-dicarbanilide-(1.2)(79455-23-5)
• EPA Substance Registry System: trans-cyclobutane-dicarbanilide-(1.2)(79455-23-5)

Safety Data

• Hazardous Substances Data: 79455-23-5(Hazardous Substances Data)

Usage

General Description

Trans-cyclobutane-dicarbanilide-(1,2) is a chemical compound with the molecular formula C8H8N2 that belongs to the cyclobutane-based compounds. It consists of two carbon atoms and two nitrogen atoms arranged in a four-membered ring. The trans-configuration of the compound means that the two carbonyl groups are on opposite sides of the ring. trans-cyclobutane-dicarbanilide-(1.2) is often used as a reagent in organic synthesis and has various applications in the field of medicinal chemistry and pharmaceuticals. Its unique structure and properties make it a valuable building block for the synthesis of more complex molecules. Additionally, it has potential applications in materials science and as a catalyst in chemical reactions.

Upstream product

• 1124-13-6 (+/-)-(1S,2S)-cyclobutane-1,2-dicarboxylic acid 
• 62-53-3 aniline 

Relevant articles and documents

Enantioseparation on Riboflavin Derivatives Chemically Bonded to Silica Gel as Chiral Stationary Phases for HPLC

Acetylated and/or 3,5-dimethylphenylcarbamated riboflavins were prepared and the resulting riboflavin derivatives as well as natural riboflavin were regioselectively immobilized on silica gel through chemical bonding at the 5'-O- or 3-N-position of the riboflavin to develop novel chiral stationary phases (CSPs) for enantioseparation by high-performance liquid chromatography (HPLC). The chiral recognition abilities of the obtained CSPs were significantly dependent on the structures of the riboflavin derivatives, the position of the chemical bonding on the silica gel, and the structures of the racemic compounds. The CSPs bonded at the 5'-O-position on the silica gel tended to well separate helicene derivatives, while the CSPs bonded at the 3-N-position composed of acetylated and 3,5-dimethylphenylcarbamated riboflavins showed a better resolving ability toward helicene derivatives and bulky aromatic racemic alcohols, respectively, and some of them were completely separated into the enantiomers. The observed difference in the chiral recognition abilities of these riboflavin-based CSPs is discussed based on the difference in their structures, including the substituents of riboflavin and the positions immobilized on the silica gel. Chirality 27:507-517, 2015.