79455-23-5

Usage

Uses

Used in Organic Synthesis:
trans-cyclobutane-dicarbanilide-(1.2) is used as a reagent in organic synthesis for its ability to form more complex molecules, making it a valuable building block in the creation of advanced chemical compounds.
Used in Medicinal Chemistry and Pharmaceuticals:
In the field of medicinal chemistry and pharmaceuticals, trans-cyclobutane-dicarbanilide-(1.2) is utilized as a key component in the development of new drugs, thanks to its unique structure and properties that can be harnessed for therapeutic purposes.
Used in Materials Science:
trans-cyclobutane-dicarbanilide-(1.2) finds applications in materials science, where its distinct structural features contribute to the development of novel materials with specific properties.
Used as a Catalyst in Chemical Reactions:
trans-cyclobutane-dicarbanilide-(1.2) is also employed as a catalyst to facilitate and enhance the efficiency of various chemical reactions, taking advantage of its reactive sites and structural characteristics.

Upstream product

• 1124-13-6 (+/-)-(1S,2S)-cyclobutane-1,2-dicarboxylic acid 
• 62-53-3 aniline 

Relevant academic research and scientific papers

Enantioseparation on Riboflavin Derivatives Chemically Bonded to Silica Gel as Chiral Stationary Phases for HPLC

Acetylated and/or 3,5-dimethylphenylcarbamated riboflavins were prepared and the resulting riboflavin derivatives as well as natural riboflavin were regioselectively immobilized on silica gel through chemical bonding at the 5'-O- or 3-N-position of the riboflavin to develop novel chiral stationary phases (CSPs) for enantioseparation by high-performance liquid chromatography (HPLC). The chiral recognition abilities of the obtained CSPs were significantly dependent on the structures of the riboflavin derivatives, the position of the chemical bonding on the silica gel, and the structures of the racemic compounds. The CSPs bonded at the 5'-O-position on the silica gel tended to well separate helicene derivatives, while the CSPs bonded at the 3-N-position composed of acetylated and 3,5-dimethylphenylcarbamated riboflavins showed a better resolving ability toward helicene derivatives and bulky aromatic racemic alcohols, respectively, and some of them were completely separated into the enantiomers. The observed difference in the chiral recognition abilities of these riboflavin-based CSPs is discussed based on the difference in their structures, including the substituents of riboflavin and the positions immobilized on the silica gel. Chirality 27:507-517, 2015.