79476-36-1Relevant academic research and scientific papers
A novel one-pot method for the preparation of pyrazoles by 1,3-dipolar cycloadditions of diazo compounds generated in situ
Aggarwal, Varinder K.,De Vicente, Javier,Bonnert, Roger V.
, p. 5381 - 5383 (2007/10/03)
A convenient one-pot procedure for the preparation of pyrazoles by 1,3-dipolar cycloaddition of diazo compounds generated in situ has been developed. Diazo compounds derived from aldehydes were reacted with terminal alkynes to furnish regioselectively 3,5-disubstituted pyrazoles. Furthermore, the reaction of N-vinylimidazole and diazo compounds derived from aldehydes gave exclusively 3-substituted pyrazoles in a one-pot process.
SYNTHESIS AND REACTIONS OF NOVEL 1,3-DIPYRIDINYL-1,3-PROPANEDIONES
Ferles, Miloslav,Liboska, Radek,Trska, Petr
, p. 1228 - 1233 (2007/10/02)
Claisen condensation leading to new 1,3-dipyridinyl-1,3-propanediones Id-If is described.The series of 3,5-dipyridinylpyrazoles IIa-IIf was completed and N-phenyl derivatives IIg-IIi, as well as isoxazoles IIIa and IIIb, were prepared.
REACTION OF 1-PYRIDYL-1,3-BUTANEDIONES AND 1,3-DIPYRIDYL-1,3-PROPANEDIONES
Ferles, Miloslav,Kafka, Stanislav,Silhankova, Alexandra,Sputova, Michaela
, p. 1167 - 1172 (2007/10/02)
Reduction of diketones I with zinc and formic acid gives monoketones II.Diketones Ia, IIIb, IIIc are converted with hydrazines to pyrazoles VIa, IVa, IVb, V.Methiodides VII are reduced with sodium borohydride to derivatives of 1-methyl-3-piperideine VIII-
