79491-49-9

Basic information

• Product Name: 5,6-DiMethoxypyridin-3-aMine
• Synonyms: 5,6-DiMethoxypyridin-3-aMine;5,6-Dimethoxy-3-pyridinamine;5,6-Dimethoxy-3-pyridinamine HCl
• CAS NO: 79491-49-9
• Molecular Formula: C₇H₁₀N₂O₂
• Molecular Weight: 154.1665
• Mol File: 79491-49-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 91-92℃ (ligroine )
• Boiling Point: 265.7 °C at 760 mmHg
• Flash Point: 114.5 °C
• Appearance: /
• Density: 1.159g/cm³
• Storage Temp.: 2-8°C
• CAS DataBase Reference: 5,6-DiMethoxypyridin-3-aMine(CAS DataBase Reference)
• NIST Chemistry Reference: 5,6-DiMethoxypyridin-3-aMine(79491-49-9)
• EPA Substance Registry System: 5,6-DiMethoxypyridin-3-aMine(79491-49-9)

Safety Data

• Hazardous Substances Data: 79491-49-9(Hazardous Substances Data)

Usage

General Description

5,6-Dimethoxypyridin-3-amine is a chemical compound belonging to the class of organic compounds known as pyridines and derivatives. Its molecular formula is C7H10N2O2. This chemical is characterized by a six-membered pyridine ring, bearing two methoxy groups on the fifth and sixth positions and an amine group at the third position. It is likely used in various industrial processes due to its basic nitrogen atoms and methoxy groups, which would make it valuable in the creation of more complex compounds through reactions such as alkylation or acylation. There is limited information available about its properties and uses, suggesting that it may be predominantly used in specialized or niche applications.

Upstream product

• 79491-45-5 2,6-dibromo-3-methoxylpyridine 
• 284040-73-9 5-chloro-1,2-dimethoxypyridine 
• 507473-22-5 2,3-dimethoxy-5-nitropyridine 
• 75711-00-1 2-chloro-3-methoxy-5-nitropyridine 
• 79491-46-6 2,6-dibromo-3-methoxy-5-nitropyridine 
• 6602-33-1 2,6-dibromopyridin-3-ol 
• 109-00-2 3-HYDROXYPYRIDINE 
• 79491-48-8 2-bromo-5,6-dimethoxy-3-nitropyridine 

Relevant articles and documents

COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS

The present invention relates to compounds that modulate cellular activities such as proliferation, differentiation, programmed cell death, migration, and chemoinvasion, by modulating protein kinase enzymatic activity, and compositions thereof, and methods of using such compounds.

COMPOUNDS FOR THE TREATMENT OF KINASE-DEPENDENT DISORDERS

Disclosed herein are compounds of Formula I'. Compounds of Formula I' inhibit, regulate and/or modulate kinase receptor, particularly Axl and Mer signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase- dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.

Mild and highly selective palladium-catalyzed monoarylation of ammonia enabled by the use of bulky biarylphosphine ligands and palladacycle precatalysts

A method for the Pd-catalyzed arylation of ammonia with a wide range of aryl and heteroaryl halides, including challenging five-membered heterocyclic substrates, is described. Excellent selectivity for monoarylation of ammonia to primary arylamines was achieved under mild conditions or at rt by the use of bulky biarylphosphine ligands (L6, L7, and L4) as well as their corresponding aminobiphenyl palladacycle precatalysts (3a, 3b, and 3c). As this process requires neither the use of a glovebox nor high pressures of ammonia, it should be widely applicable.