79492-10-7

Basic information

• Product Name: 7H-Pyrano[2,3-g]benzothiazol-7-one,2-amino-(9CI)
• Synonyms: 7H-Pyrano[2,3-g]benzothiazol-7-one,2-amino-(9CI)
• CAS NO: 79492-10-7
• Molecular Formula: C10H6N2O2S
• Molecular Weight: 218.23184
• Product Categories: BENZOTHIAZOLE
• Mol File: 79492-10-7.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 7H-Pyrano[2,3-g]benzothiazol-7-one,2-amino-(9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 7H-Pyrano[2,3-g]benzothiazol-7-one,2-amino-(9CI)(79492-10-7)
• EPA Substance Registry System: 7H-Pyrano[2,3-g]benzothiazol-7-one,2-amino-(9CI)(79492-10-7)

Safety Data

• Hazardous Substances Data: 79492-10-7(Hazardous Substances Data)

Upstream product

• 79492-08-3 2-Oxo-2H-1-benzopyrano-6-thiourea 
• 14415-44-2 6-aminocoumarin 
• 333-20-0 potassium thioacyanate 

Relevant articles and documents

Synthesis and preliminary evaluation of some substituted coumarins as anticonvulsant agents

Some new substituted coumarinylthiazolines, coumarinylthiazolidin-4-ones, and substituted chromenothiazoles were synthesized and evaluated for anticonvulsant activity. Some selected compounds were assayed against seizures induced by pentylenetetrazole (PTZ) and strychnine in mice. Compounds 3b, 6b, and 7b were the most active of the series against PTZ induced seizures. Compound 7b provided anticonvulsant activity (PD50 = 95 mg/kg, ip) at a dose 200 mg/kg compared to phenobarbital (PD50 = 16 mg/kg, ip) at a dose 30 mg/kg (90% protection). No clear correlation was observed between the antiepileptic activity and molecular lipophilicity descriptors of the tested compounds.

Some Reactions of Aminocoumarins

Aminocoumarins (Ia-f) react with potassium thiocyanate under different conditions to give benzopyranothioureas (II) and 2-aminobenzopyranothiazoles (III).With sodium cyanate some benzopyranoureas (IV) are obtained.