79510-58-0

Upstream product

• 123-54-6 acetylacetone 
• 75143-77-0 3-methyl-4-nitro-5-(2-chlorostyryl)isoxazole 
• 1123-49-5 3,5-dimethyl-4-nitroisoxazole 
• 89-98-5 2-chloro-benzaldehyde 

Downstream Products

• 78636-39-2 C₁₇H₁₆ClN₃O₄ 
• 98239-36-2 5-[2-(2-Chloro-phenyl)-2-(3,5-dimethyl-1H-pyrazol-4-yl)-ethyl]-3-methyl-4-nitro-isoxazole 
• 98239-46-4 5-[2-(2-Chloro-phenyl)-2-(3,5-dimethyl-1-phenyl-1H-pyrazol-4-yl)-ethyl]-3-methyl-4-nitro-isoxazole 
• 1242340-73-3 C₂₇H₂₁ClN₆O₇ 

Relevant academic research and scientific papers

Multi-component synthesis of methylene bis isoxazolo[4,5-b]-pyridine-N- oxides

A three component one-pot protocol was investigated for the synthesis of methylene bis isoxazolo[4,5-b]-pyridine-N-oxides from commercially available materials.

Multicomponent synthesis of spiroisoxazolines

A three-component one-pot procedure (3-MCR) was developed to assemble the spiroisoxazoline nucleus from commercially available materials. This new methodology affords the title compounds in high yields and without the use of chromatography.

Chemistry of Heterocylces: Part VIII - Synthesis of Isoxazolylethylpyrazoles

The base-catalysed addition of acetylacetone to 3-methyl-4-nitro-5-styrylisoxazoles (II) leads to the Michael adducts 3-pentane-2,4-diones (III).These β-diketones (III) undergo cyclization with hydrazine sulphate and phenylhydrazine to furnish pyrazoles (IV) and N-phenylpyrazoles (V), respectively.

Ethylene-diheterocycles: Part I - Synthesis of 5--3-methyl-4-nitroisoxazoles

Michael addition of acetylacetone to 3-methyl-4-nitro-5-styrylisoxazoles (I) in triethylamine leads to 3--2,4-pentanediones (II).The pentanediones (II) undergo cyclisation with hydroxylamine to give 5-ω