79512-78-0

Basic information

• Product Name: 3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide,(7R]
• Synonyms: 3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide,(7R)-;3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide,(7R]
• CAS NO: 79512-78-0
• Molecular Formula: C26H52 N O8 P
• Molecular Weight: 0
• Mol File: 79512-78-0.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide,(7R](CAS DataBase Reference)
• NIST Chemistry Reference: 3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide,(7R](79512-78-0)
• EPA Substance Registry System: 3,5,9-Trioxa-4-phosphapentacosan-1-aminium,7-(acetyloxy)-4-hydroxy-N,N,N-trimethyl-10-oxo-,innersalt,4-oxide,(7R](79512-78-0)

Safety Data

• Hazardous Substances Data: 79512-78-0(Hazardous Substances Data)

Usage

Uses

1-Palmitoyl-2-acetyl-sn-glycero-3-phosphorylcholine is used in the mRNA combination therapy for treatment of cancer.

Upstream product

• 112-67-4 n-hexadecanoyl chloride 
• 623-65-4 palmitic anhydride 
• 17364-16-8 1-palmitoyl-sn-glycero-3-phosphocholine 
• 108-24-7 acetic anhydride 
• 28319-77-9 L-glycero-3-phosphorylcholine 

Relevant articles and documents

Discrimination of chain positions in mixed short/long-chain glycerophosphocholines by NMR chemical shift variations

The synthesis of a series of (1,2-) mixed short/long-chain glycerophosphocholines has been performed. Starting from glycerophosphorylcholine (GPC), and using regioselective acylation in the presence of dibutyltin oxide, a set of high-purity isomeric mixed-chain phospholipids was obtained. This has allowed the development of a simple NMR method for the structural determination of the isomeric 1(2)-short-2(1)-long- diacylglycerophosphocholines. The method is based on the observation that selected protons in the two series of isomeric phospholipids undergo systematic chemical shift variations Δδ that can be ascribed to the acyl substituents on the glycerol backbone. The observed patterns can be exploited as a simple method for the discrimination of regioisomeric unsymmetrical 1,2-diacylglycerophosphocholines.

Derivatives of glycerophosphocholine and glycerophosphoethanolamine, their preparation and their use

The invention relates to new triphenylmethyl derivatives of sn-glycero-3-phosphocholine and sn-glycero-3-phosphoethanolamine of the general formula STR1 in which T denotes a triphenylmethyl group which is unsubstituted or monosubstituted or polysubstitute