795296-97-8

Upstream product

• 566202-92-4 (2R,3R)-2-(4'-benzyloxyphenyl)-5-bromo-2,3-dihydrobenzofuran-3-carboxylic acid 3-[[4'-(tert-butyldiphenylsilanyloxy)butyl]-(2'-nitrobenzenesulfonyl)amino]propyl ester 
• 566202-93-5 (2'R,3'R)-acetic acid 3-{[2'-(4''-benzyloxyphenyl)-5'-bromo-2',3'-dihydrobenzofuran-3'-carbonyl]-[4'-(tert-butyldiphenylsilanyloxy)butyl]amino}propyl ester 
• 566202-77-5 (2R,3R)-2-(4-benzyloxyphenyl)-5-bromo-2,3-dihydrobenzofuran-3-carboxylic acid 3-[4-(tert-butyldiphenylsilanyloxy)butylamino]propyl ester 
• 566202-78-6 (2R,3R)-2-(4-benzyloxyphenyl)-5-bromo-2,3-dihydrobenzofuran-3-carboxylic acid [4'-(tert-butyldiphenylsilanyloxy)butyl]-(3'-hydroxypropyl)amide 
• 566202-76-4 N-[4-(tert-butyl-diphenyl-silanyloxy)-butyl]-N-(3-hydroxy-propyl)-2-nitro-benzenesulfonamide 
• 566202-74-2 (1'R,2R,3R)-2-(4-benzyloxyphenyl)-5-bromo-2,3-dihydrobenzofuran-3-carboxylic acid 1'-methyl-2'-oxo-2'-pyrrolidin-1'-ylethyl ester 
• 566202-75-3 (2R,3R)-2-(4-benzyloxyphenyl)-5-bromo-2,3-dihydrobenzofuran-3-carboxylic acid 
• 566202-73-1 [2-(4-Benzyloxy-benzyloxy)-5-bromo-phenyl]-diazo-acetic acid (R)-1-methyl-2-oxo-2-pyrrolidin-1-yl-ethyl ester 
• 566202-91-3 (1'R)-[2-(4-benzyloxybenzyloxy)-5-bromophenyl]acetic acid 1'-methyl-2'-oxo-2'-pyrrolidin-1'-ylethyl ester 
• 566202-72-0 [2-(4-benzyloxybenzyloxy)-5-bromophenyl]acetic acid 
• 836-43-1 4-benzyloxybenzyl alcohol 
• 621-84-1 O-benzyl carbamate 
• 4397-53-9 p-benzyloxybenzaldehyde 
• 566202-80-0 (2S,3R,2'R,3'R)-3-[3'-{(3''-acetoxypropyl)-[4''-(tert-butyldiphenylsilanyloxy)butyl]carbamoyl}-2'-(4-benzyloxyphenyl)-2',3'-dihydrobenzofuran-5'-yl]-3-benzyloxycarbonylamino-2-hydroxypropionic acid methyl ester 

Downstream Products

• 566203-00-7 (3R,2'R,3'R)-3-[3'-{(3''-acetoxypropyl)-[4''-(tert-butyldiphenylsilanyloxy)butyl]carbamoyl}-2'-(4''-benzyloxyphenyl)-2',3'-dihydrobenzofuran-5'-yl]-3-{benzyloxycarbonyl-[3'-(2''-nitrobenzenesulfonylamino)propyl]amino}propionic acid methyl ester 
• 566202-85-5 3-(3-azidopropyl)-19-(4-benzyloxyphenyl)-13-pentafluorophenoxycarbonylmethyl-8-(2-nitrobenzenesulfonyl)-2-oxo-18-oxa-3,8,12-triazatricyclo[12.5.2.0^0.0]heneicosa-14⁽²¹⁾,15,17⁽²⁰⁾-triene-12-carboxylic acid benzyl ester 
• 566202-97-9 (3R,2'R,3'R)-3-[3'-{(3''-acetoxypropyl)-[4''-(tert-butyldiphenylsilanyloxy)butyl]carbamoyl}-2'-(4''-benzyloxyphenyl)-2',3'-dihydrobenzofuran-5'-yl]-3-(2''-nitrobenzenesulfonyl-[3'-(tert-butyldimethylsilanyloxy)propyl]amino)propionic acid methyl ester 
• 566202-82-2 (3R,2'R,3'R)-3-[3'-{(3''-acetoxypropyl)-[4''-(tert-butyldiphenylsilanyloxy)butyl]carbamoyl}-2'-(4''-benzyloxyphenyl)-2',3'-dihydrobenzofuran-5'-yl]-3-{benzyloxycarbonyl-[3'-(tert-butyldimethylsilanyloxy)propyl]amino}propionic acid methyl ester 
• 566202-99-1 (3R,2'R,3'R)-3-[3'-{(3''-acetoxypropyl)-[4''-(tert-butyldiphenylsilanyloxy)butyl]carbamoyl}-2'-(4''-benzyloxyphenyl)-2',3'-dihydrobenzofuran-5'-yl]-3-[benzyloxycarbonyl-(3'-hydroxypropyl)amino]propionic acid methyl ester 
• 566202-98-0 (3R,2'R,3'R)-3-[3'-{(3''-acetoxypropyl)-[4''-(tert-butyldiphenylsilanyloxy)butyl]carbamoyl}-2'-(4''-benzyloxyphenyl)-2',3'-dihydrobenzofuran-5'-yl]-3-[3'-(tert-butyldimethylsilanyloxy)propylamino]propionic acid methyl ester 
• 566202-81-1 (3R,2'R,3'R)-3-[3'-{(3''-acetoxypropyl)-[4''-(tert-butyldiphenylsilanyloxy)butyl]carbamoyl}-2'-(4''-benzyloxyphenyl)-2',3'-dihydrobenzofuran-5'-yl]-3-(2-nitrobenzenesulfonylamino)propionic acid methyl ester 
• 566202-83-3 (3R,2'R,3'R)-3-[3'-[(3''-acetoxypropyl)-(4''-hydroxybutyl)carbamoyl]-2'-(4''-benzyloxyphenyl)-2',3'-dihydrobenzofuran-5'-yl]-3-{benzyloxycarbonyl-[3'-(2''-nitrobenzenesulfonylamino)propyl]amino}propionic acid methyl ester 
• 566202-84-4 (13R,19R,20R)-3-(3'-acetoxypropyl)-19-(4'-benzyloxyphenyl)-13-methoxycarbonylmethyl-8-(2'-nitrobenzenesulfonyl)-2-oxo-18-oxa-3,8,12-triazatricyclo[12.5.2.0^0.0]heneicosa-14⁽²¹⁾,15,17⁽²⁰⁾-triene-12-carboxylic acid benzyl ester 
• 566203-06-3 3-(3-azidopropyl)-19-(4-benzyloxyphenyl)-13-carboxymethyl-8-(2-nitrobenzenesulfonyl)-2-oxo-18-oxa-3,8,12-triazatricyclo[12.5.2.0^0.0]heneicosa-14⁽²¹⁾,15,17⁽²⁰⁾-triene-12-carboxylic acid benzyl ester 
• 566203-04-1 3-(3-azidopropyl)-19-(4-benzyloxyphenyl)-13-methoxycarbonylmethyl-8-(2-nitrobenzenesulfonyl)-2-oxo-18-oxa-3,8,12-triazatricyclo[12.5.2.0^0.0]heneicosa-14⁽²¹⁾,15,17⁽²⁰⁾-triene-12-carboxylic acid benzyl ester 
• 566202-88-8 O-benzyloxy-N₁-benzyloxycarbonyl-N₂-nitrobenzenesulfonyl-ephedradine A 
• 566203-02-9 19-(4-benzyloxyphenyl)-3-(3-hydroxypropyl)-13-methoxycarbonylmethyl-8-(2-nitrobenzenesulfonyl)-2-oxo-18-oxa-3,8,12-triazatricyclo[12.5.2.0^0.0]heneicosa-14⁽²¹⁾,15,17⁽²⁰⁾-triene-12-carboxylic acid benzyl ester 
• 566202-96-8 (3R,2'R,3'R)-3-[3'-{(3''-acetoxypropyl)-[4''-(tert-butyldiphenylsilanyloxy)butyl]carbamoyl}-2'-(4''-benzyloxyphenyl)-2',3'-dihydrobenzofuran-5'-yl]-3-aminopropionic acid methyl ester 

Relevant academic research and scientific papers

Total synthesis of (-)-ephedradine A: An efficient construction of optically active dihydrobenzofuran-ring via C-H insertion reaction

The stereocontrolled total synthesis of (-)-ephedradine A (1) has been accomplished. Construction of optically active dihydrobenzofuran-ring was performed by a novel asymmetric C-H insertion reaction. After an intramolecular ester-amide exchange reaction and a Sharpless asymmetric aminohydroxylation reaction, construction of the complex macrocyclic ring was performed by Ns-strategy and an intramolecular aza-Wittig reaction. Graphical Abstract.