795296-98-9Relevant academic research and scientific papers
An efficient synthesis of optically active trans-2-Aryl-2,3-dihydrobenzofuran-3-carboxylic acid esters via C-H insertion reaction
Kurosawa, Wataru,Kan, Toshiyuki,Fukuyama, Tohru
, p. 1028 - 1030 (2007/10/03)
Optically active trans-2-Aryl-2,3-dihydrobenzofuran-3-carboxylic acid esters were synthesized by intramolecular C-H insertion reaction. Upon treatment with a catalytic amount of Rh2(R-DOSP)4, aryldiazoester 8c possessing a chiral auxiliary underwent C-H insertion reaction to give 9c in high yield and in high selectivity (84% yield, 86% de).
