79537-70-5

Basic information

• Product Name: (3-ACETYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER
• Synonyms: (3-ACETYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER;TERT-BUTYL 3-ACETYLPHENYLCARBAMATE;tert-Butyl (3-acetylphenyl)
• CAS NO: 79537-70-5
• Molecular Formula: C13H17NO3
• Molecular Weight: 235.28
• Mol File: 79537-70-5.mol
• Article Data: 14

Chemical Properties

• Appearance: /
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (3-ACETYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: (3-ACETYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(79537-70-5)
• EPA Substance Registry System: (3-ACETYL-PHENYL)-CARBAMIC ACID TERT-BUTYL ESTER(79537-70-5)

Safety Data

• Hazardous Substances Data: 79537-70-5(Hazardous Substances Data)

Usage

General Description

(3-Acetyl-phenyl)-carbamic acid tert-butyl ester, also known as N-Boc-3-acetylphenylcarbamic acid, is a chemical compound used in the synthesis of pharmaceutical drugs and organic compounds. Its molecular formula is C13H15NO4, and it is commonly used as an intermediate in the production of various pharmaceuticals. The compound is a white to light yellow solid with a molecular weight of 249.26 g/mol. It is typically used in organic synthesis as a reagent for the formation of amides and esters. Additionally, it is also utilized in the production of photoinitiators for photopolymerization reactions. The compound is considered to be stable and non-reactive under normal conditions.

Upstream product

• 431-03-8 dimethylglyoxal 
• 143390-49-2 iodo-3-(tert-butyloxycarbonylamino)benzene 
• 24424-99-5 di-tert-butyl dicarbonate 
• 99-03-6 1-(3-aminophenyl)ethanone 
• 4248-19-5 tert-butyl carbazate 
• 99-02-5 3'-Chloroacetophenone 
• 2142-63-4 1-(3-Bromophenyl)ethanone 
• 70334-60-0 3-(azidophenyl) methyl ketone 

Downstream Products

• 108714-19-8 (E)-1-(3′-aminophenyl)-3-phenylprop-2-en-1-one 

Relevant articles and documents

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Contra-thermodynamic E → Z isomerization of cinnamamides via selective energy transfer catalysis

A bio-inspired, photocatalytic E → Z isomerization of cinnamides is reported using inexpensive (?)-riboflavin (vitamin B2) under irradiation at λ = 402 nm. This operationally simple transformation is compatible with a range of amide derivatives including –NR2, –NHSO2R and N(Boc)2 (up to 99:1 Z:E). Selective energy transfer from the excited state photocatalyst to the starting E-isomer ensures that directionality is achieved: The analogous process with the Z-isomer is inefficient due to developing allylic strain causing chromophore deconjugation. This is supported by X-ray analysis and Stern-Volmer photo-quenching studies. Preliminary validation of the method in manipulating the conformation of a simple model Leu-enkephalin penta-peptide is disclosed via the incorporation of a cinnamamide-based amino acid.

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