79557-60-1Relevant academic research and scientific papers
Hydroxyacetophenone-derived antagonists of the peptidoleukotrienes
Brown,Bersntein,Cronk,Dossett,Hebbel,Maduskuie Jr.,Shapiro,Vacek,Yee,Willard,Krell,Snyder
, p. 807 - 826 (2007/10/02)
Considerations of the possible similarities between leukotriene D4 and its prototypical antagonist, FPL 55712, led to the development of a new series of leukotriene antagonists incorporating a hydroxyacetophenone group (e.g., the toluic acids 1
Leukotriene receptor antagonists. 1. Synthesis and structure-activity relationships of alkoxyacetophenone derivatives
Marshall,Goodson,Cullinan,Swanson-Bean,Haisch,Rinkema,Fleisch
, p. 682 - 689 (2007/10/02)
A series of derivatives of 2,4-dihydroxy-3-propylacetophenone were prepared and examined for their ability to block leukotriene D4 (LTD4) induced contraction of guinea pig ileum. Straight-chain carboxylic acids where the carboxyl gro
