79557-90-7

Upstream product

• 89-86-1 4-hydroxysalicylic acid 
• 100-39-0 benzyl bromide 
• 100-44-7 benzyl chloride 

Downstream Products

• 4707-43-1 4-((2,4-dihydroxybenzoyl)oxy)-2-hydroxybenzoic acid 
• 944282-94-4 2-hydroxy-4-(4-n-tetradecyloxybenzoyloxy)benzoic acid 
• 944282-93-3 benzyl 2-hydroxy-4-(4-n-tetradecyloxybenzoyloxy)benzoate 

Relevant academic research and scientific papers

Synthesis and antibacterial evaluation of anziaic acid and its analogues as topoisomerase i inhibitors

Naturally occurring anziaic acid has very recently been reported as a topoisomerase I inhibitor with antibacterial activity. Herein total synthesis of anziaic acid and its structural analogues is described and the preliminary structure-activity relationship (SAR) has been developed based on topoisomerase inhibition and whole cell antibacterial activity.

DIACYLETHYLENEDIAMINE COMPOUND

[Problem] A compound which is useful as an anti-obesity agent is provided. [Means for Solution] The present inventors have investigated a compound having a DGAT1 inhibitory action, which is promising as an active ingredient of a pharmaceutical composition

Liquid crystalline and nonlinear optical properties of bent-shaped compounds derived from 3,4′-biphenylene

The synthesis of different bent-core molecules derived from 3,4′-biphenylene bearing azo, azoxy, imine or ester linkages in their lateral structures is reported. Structure-activity relationships for their liquid crystalline behaviour are discussed. SmCP, USmCP and Colob mesophases are found depending on the type and number of these connecting units. The sequence ester ≈ azoxy > imine > azo can be proposed for the mesophase range, with significant differences observed in terms of mesopahase stabilization. SHG studies on these compounds give nonlinear coefficients in the range of 1-8 pm V-1. The molecular origin for these values is analyzed semi-quantitatively. It was concluded that the SHG performance of bent-core mesogens in general can still be increased substantially. An approach to improve the properties of these materials is briefly outlined. The Royal Society of Chemistry 2007.

A simple and effective method for chemoselective esterification of phenolic acids

A new method for efficient and chemoselective esterification of phenolic acids in KHCO3/alkyl halide/DMF reaction system is described, by which a series of phenoic acid esters were obtained in excellent yields.

Silicone-containing derivatives of salicylic acid which have desquamating properties

The invention relates to novel compounds of the organosiloxane and organosilane type, bearing at least one function derived from salicylic acid. These novel products have, in particular, desquamating and/or anti-aging properties and may be used in topical

Diaromatic compounds derived from a salicylic unit and their use in human and veterinary medicine and in cosmetics

Diaromatic compounds, characterized in that they correspond to the following general formula: STR1 in which: R1 is --CH3, --CH2 OH, --COR8 or --CH2 OCOR9, R8 is H, OH, --OR10, --N(rr') or alkyl, R10 is alkyl, alkenyl, aryl or aralkyl, r and r' being H, alkyl, aryl, aralkyl, etc., r and r' together form a heterocycle, R9 is alkyl, alkenyl or a sugar residue, R2 and R3 are --OR11 or --OCOR11, R11 is H, alkyl, fluoroalkyl, aryl or aralkyl, R3 in addition being H, R4 is H, OH, alkyl, alkoxy, F, Cl or --CF3, R5 and R7 are H, OH, alkoxy, α-substituted alkyl or α,α'-disubstituted alkyl, etc., R6 is H, OH, alkyl, alkoxy, cycloalkyl, etc., R5 and R7 cannot simultaneously be OH or alkoxy and R4, R5, R6 and R7 cannot simultaneously be H, R5 and R6 or R6 and R 7 can form, with the aromatic ring, a ring with 5 or 6 members, X is chosen from amongst: (i) --C(R13 R14)--C(R16 R18)--W--, (ii) --C(R14 R16)--W--C(R18 R19)--, (iii) --C(R13 R14)--C(R15 R16)--C(R18 R20)--, (iv) --CR17 =CR21 --C(R13 R14)--, W is O, --NR12 or S(O)n, n=0, 1 or 2, R13, R15 and R20 are H, --OR11, --OCOR11 etc. , R14, R16, R18 and R19 are H, aralkyl, alkyl, etc., when X is (i) R13 and R14 can form =N--OR11 or =N--OCOR11, when X is (iii) or (iv), R14, R16 and R18 are also --OR11 or --OCOR11, or R13, R14 or R15, R16 taken together can form =NOR11 or =N--OCOR11, R12 is H, alkyl, aralkyl, alkenyl, alkynyl or fluoroalkyl, R17 is H, hydroxyl, alkyl or alkoxy, R21 is H or alkyl, and the salts of the compounds of formula (I).

Bi-aromatic esters, a process for their preparation and their use in human or veterinary medicine and in cosmetic compositions

Bi-aromatic esters have the formula STR1 wherein R1 represents H, OH, --CH3, --CH2 OH, --CH(OH)CH3, --COOR9, STR2 or SO2 R10 ; R9 represents H, C1 -C6

Benzamide derivatives

Benzamide derivatives of the formula:- STR1 wherein R1 represents a fluorine, chlorine or bromine atom, or an alkyl, alkoxy, alkylthio, alkylsulphonyl, alkanoylamino, alkylamino or alkylsulphamoyl group, each such group containing from 1 to 6 carbon atoms, a dialkylsulphamoyl, dialkylamino or dialkylcarbamoyl group (wherein the two alkyl groups may be the same or different and each contains from 1 to 4 carbon atoms), an alkanoyl, alkoxycarbonyl, alkoxycarbonylamino or alkylcarbamoyl group containing from 2 to 6 carbon atoms, or a hydroxy, formyl, nitro, trifluoromethyl, aryl, benzyloxycarbonylamino, amino, sulphamoyl, cyano, tetrazol-5-yl, carboxy, carbamoyl or aroyl group, and n represents an integer 1, 2 or 3, are new compounds possessing pharmacological properties, in particular properties of value in the treatment of respiratory disorders manifested by the interaction of tissue-fixed antibodies with specific antigens.