79557-90-7Relevant articles and documents
Synthesis and antibacterial evaluation of anziaic acid and its analogues as topoisomerase i inhibitors
Lin, Hao,Annamalai, Thirunavukkarasu,Bansod, Priyanka,Tse-Dinh, Yuk-Ching,Sun, Dianqing
supporting information, p. 1613 - 1618 (2013/12/04)
Naturally occurring anziaic acid has very recently been reported as a topoisomerase I inhibitor with antibacterial activity. Herein total synthesis of anziaic acid and its structural analogues is described and the preliminary structure-activity relationship (SAR) has been developed based on topoisomerase inhibition and whole cell antibacterial activity.
Liquid crystalline and nonlinear optical properties of bent-shaped compounds derived from 3,4′-biphenylene
Pintre, Inmaculada C.,Gimeno, Nelida,Serrano, Jose Luis,Ros, M. Blanca,Alonso, Ibon,Folcia, Cesar L.,Ortega, Josu,Etxebarria, Jesus
, p. 2219 - 2227 (2008/02/11)
The synthesis of different bent-core molecules derived from 3,4′-biphenylene bearing azo, azoxy, imine or ester linkages in their lateral structures is reported. Structure-activity relationships for their liquid crystalline behaviour are discussed. SmCP, USmCP and Colob mesophases are found depending on the type and number of these connecting units. The sequence ester ≈ azoxy > imine > azo can be proposed for the mesophase range, with significant differences observed in terms of mesopahase stabilization. SHG studies on these compounds give nonlinear coefficients in the range of 1-8 pm V-1. The molecular origin for these values is analyzed semi-quantitatively. It was concluded that the SHG performance of bent-core mesogens in general can still be increased substantially. An approach to improve the properties of these materials is briefly outlined. The Royal Society of Chemistry 2007.
Silicone-containing derivatives of salicylic acid which have desquamating properties
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, (2008/06/13)
The invention relates to novel compounds of the organosiloxane and organosilane type, bearing at least one function derived from salicylic acid. These novel products have, in particular, desquamating and/or anti-aging properties and may be used in topical