79561-72-1Relevant articles and documents
Synthesis of enantiomerically pure (+)- and (-)-protected 5-aminomethyl-1,3-oxazolidin-2-one derivatives from allylamine and carbon dioxide
Fernandez, Isabelle,Munoz, Luis
, p. 2548 - 2557 (2007/10/03)
The stereoselective synthesis of enantiomerically pure (5R)- and (5S)-aminomethyl-oxazolidinones with different protecting groups have been carried out from an allyl amine as the source of the carbon backbone. The key reaction is the high yield iodiocyclization of enantiomerically pure allylphenethyl amine in the presence of carbon dioxide.
A NEW PROTECTING GROUP FOR AMINES. SYNTHESIS OF ANTICAPSIN FROM L-TYROSINE
Laguzza, Bennett C.,Ganem, Bruce
, p. 1483 - 1486 (2007/10/02)
An acid and base-stable, nucleophile-resistant protecting group for primary amines and α-amino acids is described which has been used in a synthesis of the title compound.