79563-72-7Relevant academic research and scientific papers
Acid-catalyzed reactions of epoxides for atmospheric nanoparticle growth
Xu, Wen,Gomez-Hernandez, Mario,Guo, Song,Secrest, Jeremiah,Marrero-Ortiz, Wilmarie,Zhang, Annie L.,Zhang, Renyi
supporting information, p. 15477 - 15480 (2015/02/18)
Although new particle formation accounts for about 50% of the global aerosol production in the troposphere, the chemical species and mechanism responsible for the growth of freshly nucleated nanoparticles remain largely uncertain. Here we show large size
Bacterial biotransformation of isoprene and related dienes
Boyd, Derek R.,Clarke, David,Cleij, Marcel C.,Hamilton, John T.G.,Sheldrake, Gary N.
, p. 673 - 685 (2007/10/03)
The bacterium Pseudomonas putida ML 2 was used in the oxidative biodegradation of the acyclic dienes isoprene, trans-piperylene, cis-piperylene, and 1,3-butadiene. Regioselective dioxygenase-catalyzed dihydroxylation of alkenes yielded vicinal diols in the preferred sequence monosubstituted 〉 cis-disubstituted 〉 gem-disubstituted 〉 trans-disubstituted. The isolated diol metabolites had an excess of the R configuration (9-97% ee), and further diol oxidation was controlled by addition of propylene glycol as an inhibitor. Stereoselectivity using the ML2 strain resulted from both enzymatic asymmetric alkene dihydroxylation and kinetic resolution of diols. Enantioselective oxidation of the allylic secondary alcohol group of R configuration yielded the corresponding unsaturated ketoalcohol; the residual diol was recovered with a large excess (≥ 93% ee) of the S configuration. In addition to the enzymatic diene oxidation steps yielding unsaturated diols and ketoalcohols, evidence was also found of enzymatic alkene hydrogenation to yield saturated ketoalcohols and diols.
