79581-93-4Relevant academic research and scientific papers
Evaluation of antifungal and antibacterial activities of monoesters of succinic anhydride
Iqbal, Muhammad,Baloch, Imam Bakhsh,Baloch, Musa Kaleem
, p. 131 - 136 (2014/03/21)
Monoester of succinic acid (1-29), synthesised and characterised at our laboratory, were investigated with reference to their antifungal and antibacterial activities. The results concluded that though almost all the compounds were bioactive but the degree
An efficient method for the preparation of benzyl γ-ketohexanoates
Iqbal, Muhammad,Baloch, Imam B.,Baloch, Musa K.
, p. 444 - 455 (2013/08/24)
Twenty acid chlorides, 4-(mono/di-benzyloxy)-4-ketobutanoyl chlorides (Ia-XXa) were synthesised by the reaction of monoesters of succinic acid with thionyl chloride. The product thus obtained (4-benzyloxy-4-ketobutanoyl chlorides) was treated with diethyl
Estrogen derivative having carriers to bone
-
, (2008/06/13)
A novel estrogen derivative represented by the formula: STR1 is useful for treating or preventing diseases caused by estrogen deficiency.
Spermexatin and Spermexatol: New Synthetic Spermidine-Based Siderophore Analogues
Sharma, Sushil K.,Miller, Marvin J.,Payne, Shelley M.
, p. 357 - 367 (2007/10/02)
Syntheses of hexanediamine-based dihydroxamate (Hexamate), spermidine-based trihydroxamate (Spermexatins), and spermidine-based mixed siderophore analogues (Spermexatols) are described.Key intermediates include the N-hydroxysuccinimide esters of various hydroxamic acids, e.g., malonohydroxamate, succinohydroxamate, and glutarohydroxamate.These intermediates were synthesized, characterized, and incorporated as the ligating chains on spermidine.Also, mixed iron chelating compounds (Spermexatols) with both catechol and hydroxamic acid side chains were synthesized.Thereagent carbobenzoxyimidazole was employed to distinguish between the primary and secondary amino groups of spermidine.The ability of these iron chelators to stimulate microbial growth is also described.
